Patents Assigned to VAXNEWMO LLC
  • Glycosylated ComP pilin variants, methods of making and uses thereof
    Patent number: 11932670
    Abstract: Provided herein are glycosylated ComP proteins, fragments and fusion proteins thereof, and methods of making, for example, for use in the production of conjugate vaccines. Also provided herein are conjugate vaccines against diseases including bacterial diseases.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: March 19, 2024
    Assignee: VaxNewMo LLC
    Inventors: Christian Harding, Mario Feldman
  • Acinetobacter O-oligosaccharyltransferases and uses thereof
    Patent number: 11497804
    Abstract: The present application provides methods and uses of O-oligosaccharyltransferase (O-OTases) for generating vaccines. In particular, the present application provides a method of synthesizing a glycoprotein comprising glycosylation of pilin-like protein ComP using a Pg1LComP O-OTase. Uses of glycoproteins synthesized by glycosylating ComP using Pg1LComP O-OTase, particularly for the preparation of vaccines and the like, including a vaccine to Streptococcus, is also provided.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: November 15, 2022
    Assignee: VaxNewMo LLC
    Inventors: Mario Feldman, Mohamed Adel Nasr
  • Acinetobacter o-oligosaccharyltransferases and uses thereof
    Patent number: 10869918
    Abstract: The present application provides methods and uses of O-oligosaccharyltransferase (O-OTases) for generating vaccines. In particular, the present application provides a method of synthesizing a glycoprotein comprising glycosylation of pilin-like protein ComP using a PglLComP O-OTase. Uses of glycoproteins synthesized by glycosylating ComP using PglLComP O-OTase, particularly for the preparation of vaccines and the like, including a vaccine to Streptococcus, is also provided.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: December 22, 2020
    Assignee: VAXNEWMO LLC
    Inventors: Mario Feldman, Mohamed Adel Nasr
  • Acinetobacter O-oligosaccharyltransferases and uses thereof
    Patent number: 10265391
    Abstract: The present application provides methods and uses of O-oligosaccharyltransferase (O-OTases) for generating vaccines. In particular, the present application provides a method of synthesizing a glycoprotein comprising glycosylation of pilin-like protein ComP using a PglLComP O-OTase. Uses of glycoproteins synthesized by glycosylating ComP using PglLComP O-OTase, particularly for the preparation of vaccines and the like, including a vaccine to Streptococcus, is also provided.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: April 23, 2019
    Assignee: VAXNEWMO LLC
    Inventors: Mario Feldman, Mohamed Adel Nasr
  • ACINETOBACTER O-OLIGOSACCHARYLTRANSFERASES AND USES THEREOF
    Publication number: 20180050101
    Abstract: The present application provides methods and uses of O-oligosaccharyltransferase (O-OTases) for generating vaccines. In particular, the present application provides a method of synthesizing a glycoprotein comprising glycosylation of pilin-like protein ComP using a Pg1LComP O-OTase. Uses of glycoproteins synthesized by glycosylating ComP using Pg1LComP O-OTase, particularly for the preparation of vaccines and the like, including a vaccine to Streptococcus, is also provided.
    Type: Application
    Filed: February 26, 2016
    Publication date: February 22, 2018
    Applicant: VAXNEWMO LLC
    Inventors: Mario FELDMAN, Mohamed Adel NASR