Abstract: A spray coating machine and process accommodates coating pans of various sizes and simplifies cleaning after particulate material in the pan is coated. A selected pan is supported on a trolley carried by a wheeled cart. After the cart is positioned adjacent the coating machine, the trolley and pan are extended into the machine, and then the pan lifted for support by a rotatable drive shaft and castors. The trolley is then removed from the machine, and the door is closed so that the coating process can commence. When coating is complete, the door is opened, and the trolley extended into the machine under the pan and raised for removal of the castors. Then, the trolley and pan are withdrawn from the machine. The trolley does not need cleaning after spraying, since the trolley is outside the machine during spraying of the coating solution.

Abstract: A spray coating machine and process accommodates coating pans of various sizes and simplifies cleaning after particulate material in the pan is coated. A selected pan is supported on a trolley carried by a wheeled cart. After the cart is positioned adjacent the coating machine, the trolley and pan are extended into the machine, and then the pan lifted for support by a rotatable drive shaft and castors. The trolley is then removed from the machine, and the door is closed so that the coating process can commence. When coating is complete, the door is opened, and the trolley extended into the machine under the pan and raised for removal of the castors. Then, the trolley and pan are withdrawn from the machine. The trolley does not need cleaning after spraying, since the trolley is outside the machine during spraying of the coating solution.

Abstract: A steam or reactant system is provided for a roller compactor to provide improved compaction or functional characteristic of powdered materials, such as active pharmaceutical ingredients. The steam or reactants can be added through conduits terminating in nozzles adjacent the nip zone of the compaction rollers. The injection nozzles can be directed tangentially from the above the rollers or laterally from the sides of the rollers. In one embodiment, the moisture is in the form of steam. The resulting compacting sheet has improved compaction characteristics and reduced compression variability.

Abstract: A Wurster processor and a powder feed system are coupled via an eductor so as to supply dry powder through the air diverter sleeve of the Wurster for discharging onto the circulating particles during operation of the Wurster. Agglomeration and aggregation of the particles is eliminated or minimized by isolating or separating the liquid spray by the spray gun from the dry powder.

Abstract: A hinge dampening device is provided for a granulation processor having a bowl and a lid. A dampening device includes first and second spaced apart hinge supports fixed to the bowl and a pin extending through the lid collar residing between the hinge supports. The first end of the pin is fixed to the first hinge support, and a second end of the pin extends through the second hinge support. An adjustable compressive force is applied axially to the hinge supports and lid collar to create frictional resistance to rotation of the lid. The rotational resistance provides controlled opening and closing of the lid.

Abstract: An overpressure absorption mechanism is provided for a fluid bed processor. The mechanism includes spring assemblies mounted in the legs of the processor. The arms of the lower housing section extend into the legs and are supported on the springs. If an overpressure condition arises within the processor, the springs compress to allow movement between the housing sections to allow engagement of clamping rings which contain the over pressure condition.

Abstract: The fluidized bed processor of the present invention includes an internal filter assembly with a rack and a cartridge-type filter supported at the lower end by a bracket. The rack includes an elongated rod extending through the filter. An end cap is provided on the lower end of the rod for normal sealing engagement with the filter bracket. During normal operation of the processor, the upper and lower ends of the filter are sealed. During or after cleaning of the filter, the rack is lowered, and a spring separates the filter and support bracket from the end cap so as to create a gap for drainage of cleaning fluid.

Abstract: The improved rotor processor of the present invention includes a stator with a rotatable rotor defining a rotor chamber in which particles are circulated for coating or layering. A spray gun mounted to the stator adjacent the rotor directs liquid into the rotor chamber, while a powder feed system mounted in the stator adjacent the rotor directs dry powder into the rotor chamber. The spray gun and powder feed system are spaced apart circumferentially so as to define a spray zone and a separate powder zone through which the circulating particles repeatedly and sequentially pass. The powder feed system includes a feed screw conveyor, an eductor, and a flexible conduit for delivering micronized powders, such as polymers or glidants, to the rotor chamber.

Abstract: A rotor processor includes a stator chamber and a rotor mounted for rotation within the chamber. The rotor has a perimeter edge spaced closely to the interior wall of the chamber so as to define a slit or gap there between. The rotor is slidably mounted upon a rotor shaft, for movement between raised and lowered positions during operation of the processor, so as to automatically adjust the dimension of the slit, without operator intervention. As air flows from a plenum beneath the rotor, through the slit, and into the chamber, a pressure differential is created, which provides a lifting force to raise the rotor. The pressure drop is maintained relatively constant at a predetermined level after a lifting equilibrium force is achieved, regardless of the air flow volume.

Abstract: A rotor processor includes a stator chamber and a rotor mounted for rotation within the chamber. The rotor has a perimeter edge spaced closely to the interior wall of the chamber so as to define a slit or gap there between. The rotor is slidably mounted upon a rotor shaft, for movement between raised and lowered positions during operation of the processor, so as to automatically adjust the dimension of the slit, without operator intervention. As air flows from a plenum beneath the rotor, through the slit, and into the chamber, a pressure differential is created, which provides a lifting force to raise the rotor. The pressure drop is maintained relatively constant at a predetermined level after a lifting equilibrium force is achieved, regardless of the air flow volume.

Abstract: A pump assembly includes a base plate upon which a drive motor is mounted and pump plate upon which first and second pumps are mounted. The pump plate is adjustably mounted on the base plate so as to be moveable between first and second positions relative to the base plate. In the first position, the first pump is operatively engaged with the motor and the second pump is disengaged from the motor. In the second position, the second pump is operatively engaged with the motor and the first pump is disengaged from the motor. An operator can quickly and easily change from one pump to the other simply by loosening thumbnuts, repositioning the pump plate on the base plate, and tightening the nuts.

Abstract: A screw feeder is provided for a powder roller compactor machine. The machine includes a hopper for holding powder and a pair of rollers for compacting the powder. A screw feeder transfers powder from the hopper to the rollers. The screw feeder includes an upper tapered section with a tapered shaft and a lower straight section with a straight shaft. Auger flighting is provided on the tapered and straight sections of the screw feeder. The auger flighting preferably has a fixed depth along the length of the screw feeder.

Abstract: A discrete volume vacuum sampling device is provided with a vacuum tube, a sample tube, and a sample container. The container defines a discrete volume of product to be sampled from a product bed within a processing machine. The sampler tube extends between the container and the machine containing the product to be sampled. When a vacuum is applied through the vacuum tube, a door on the container is pulled shut, thereby increasing air velocity in the sampler tube, so as to draw product from the bed upwardly through the sampler tube and into the container. When the container is full, the vacuum is stopped, such that the weight of the product in the container pushes the door open for discharge of the discrete volume of product sample, while product remaining within the sampler tube is discharged back into the bed of material within the machine.

Abstract: Systems are arranged to provide a user information which relates to objects of interest. A user may point a hand held device toward an object to address it. The device determines which objects are being addressed by making position and attitude measurements and further a reference and search of a database containing preprogrammed information relating to objects. Information relating to objects determined as objects presently being addressed is thereafter presented at a user interface. Devices of these systems include a point reference, a direction reference, a position determining support, attitude determining support, a computer processor and database, and a user interface. Methods of systems include the steps of addressing an object, determining position and attitude, searching a database, and presenting information to a user.

Abstract: The improved Wurster of the present invention includes an air diverter which supplies a flow of air in a radial direction adjacent the spray nozzle body and spray nozzle, so as to force the product away from the nozzle during the spraying process. The air diverter includes a sleeve with air passages therein, a manifold connected to the sleeve and to a source of secondary pressurized air or gas, and a collar to mount the assembled air diverter onto the perforated plate of the Wurster apparatus. In operation, the air diverter allows the spray pattern from the nozzle to more fully develop, allows more complete atomization of the spray solution, and allows for higher spray rates with little or no agglomeration of the product.

Abstract: The improved Wurster of the present invention includes an air diverter which supplies a flow of air in a radial direction adjacent the spray nozzle body and spray nozzle, so as to force the product away from the nozzle during the spraying process. The air diverter includes a sleeve with air passages therein, a manifold connected to the sleeve and to a source of secondary pressurized air or gas, and a collar to mount the assembled air diverter onto the perforated plate of the Wurster apparatus. In operation, the air diverter allows the spray pattern from the nozzle to more fully develop, allows more complete atomization of the spray solution, and allows for higher spray rates with little or no agglomeration of the product.

Abstract: The improved Wurster of the present invention includes an air diverter which supplies a flow of air in a radial direction adjacent the spray nozzle body and spray nozzle, so as to force the product away from the nozzle during the spraying process. The air diverter includes a sleeve with air passages therein, a manifold connected to the sleeve and to a source of secondary pressurized air or gas, and a collar to mount the assembled air diverter onto the perforated plate of the Wurster apparatus. In operation, the air diverter allows the spray pattern from the nozzle to more fully develop, allows more complete atomization of the spray solution, and allows for higher spray rates with little or no agglomeration of the product.