Abstract: The present invention relates to pharmaceutical compositions and their uses in therapy. In particular, the invention relates to compositions comprising methotrexate, preferably wherein the compositions are for administration via the inhaled or intranasal route.
Type:
Application
Filed:
November 17, 2006
Publication date:
February 18, 2010
Applicant:
Vectura Group PLC
Inventors:
Andrew John McGlashan Richards, Peter Strong, Ann Gail Hayes, David Alexander Vodden Morton
Abstract: A blister piercing element for puncturing the Hd of a blister containing a dose of medicament for inhalation by a user is disclosed. The piercing element comprising an outlet opening for the passage of medicament entrained in an airflow out of the blister and, a piercing head extending beyond and overhanging the opening that cuts a flap in a lid of a blister and pushes it away from the opening during insertion.
Type:
Application
Filed:
April 13, 2006
Publication date:
April 9, 2009
Applicant:
Vectura Group PLC
Inventors:
Quentin John Harmer, Roger William Clarke, Stephen William Eason, Andreas Mark Meliniotis
Abstract: The present invention relates to new pharmaceutical formulations comprising pharmaceutically active agents which can induce one or more involuntary coughs in a patient when administered as conventional formulations and/or via conventional routes. Formulations are provided comprising a cough-inducing pharmaceutically active agent, wherein the formulation may be administered by pulmonary inhalation without inducing a cough. Alternatively, formulations are provided for administering the cough-inducing active agent via an alternative route.
Type:
Application
Filed:
May 22, 2008
Publication date:
March 12, 2009
Applicant:
Vectura Group plc
Inventors:
Mark Jonathan Main, Martin James Oliver, Timothy Wright
Abstract: A blister pack comprising a plurality of spaced blister cavities each configured to receive and store an individual dose of medicament for inhalation by a user is disclosed. The pack includes a foil layer and an outer polymer layer and each blister cavity, or a number of blister cavities, are separated from an adjacent blister cavity, or number of adjacent blister cavities, by a region of weakness formed by substantially removing or displacing a portion of the outer polymer layer from the foil layer.
Type:
Application
Filed:
April 13, 2006
Publication date:
June 12, 2008
Applicant:
Vectura Group PLC
Inventors:
Andreas Mark Meliniotis, Peter Alan Evans, Stephen William Eason, Quentin John Harmer