Abstract: Pharmaceutical compositions comprising 1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7-methoxy-8-hydroxy-5H-2,3-benzodiazepine; or a pharmaceutically acceptable salt thereof. The compositions are used for treating, preventing or delaying the onset of disorders mediated by LTB4, TXA2 or adenosine.
Type:
Grant
Filed:
December 3, 2003
Date of Patent:
June 29, 2010
Assignee:
Vela Acquisition Corporation
Inventors:
Herbert W. Harris, Robert F. Kucharik, Steven M. Leventer
Abstract: Methods for the racemization of an enantiomer of a 2,3-benzodiazepine molecule into the corresponding racemic mixture under either basic or acidic conditions are described. Furthermore, the invention relates to the conversion of an enantiomer of tofisopam or its metabolites to the corresponding opposite enantiomer.
Type:
Grant
Filed:
May 23, 2005
Date of Patent:
June 2, 2009
Assignee:
Vela Acquisition Corporation
Inventors:
Yong Victoria Wei, Naidaong Ye, Kimm Galbraith, Jianfeng Shi, Wuyi Wang, Yungen Xu, Mallikarjun Reddy Ravi