Abstract: Provided herein are immunoconjugates comprising an anti-ROR1 antibody or an antigen-binding fragment thereof and an exatecan moiety or an analog thereof. These immunoconjugates are useful for treating ROR1-expressing cancers.
Type:
Application
Filed:
July 8, 2021
Publication date:
September 21, 2023
Applicant:
Velosbio Inc.
Inventors:
Brian Lannutti, Katti Jessen, Xin Guo, Mira Ko, Jeffry D. Watkins, Stephanie Louise Johnson, Colin Martin McKee
Abstract: This invention relates to anti-ROR1 antibodies and methods of using them in treating diseases and conditions related to ROR1 activity, e.g., cancer.
Type:
Application
Filed:
February 5, 2021
Publication date:
January 26, 2023
Applicant:
VelosBio Inc.
Inventors:
Jeffry D. WATKINS, Thanh-Trang VO, J. Monty WATKINS
Abstract: This invention relates to bispecific binding molecules that bind to ROR1 and CD3, and methods of using them to treat diseases and conditions such as cancer.
Type:
Application
Filed:
May 22, 2020
Publication date:
July 21, 2022
Applicant:
VelosBio Inc.
Inventors:
Jeffry D. Watkins, Katti Jessen, Mira Ko, Brian Lannutti, Thanh-Trang Vo, J. Monty Watkins
Abstract: Provided herein are methods for treating a cancer patient with immunoconjugates comprising an anti-ROR1 antibody or an antigen-fragment fragment thereof and a drug moiety.
Type:
Application
Filed:
February 1, 2020
Publication date:
May 19, 2022
Applicant:
VelosBio Inc.
Inventors:
Langdon Miller, Brian Lannutti, Katti Jessen
Abstract: Provided herein are immunoconjugates comprising an anti-ROR1 antibody or an antigen-fragment fragment thereof and a drug moiety. These immunoconjugates are useful for treating ROR1 expressing cancers.
Type:
Application
Filed:
November 11, 2021
Publication date:
May 5, 2022
Applicant:
VelosBio Inc.
Inventors:
Brian Lannutti, Katti Jessen, Thanh-Trang Vo, Jeffry Dean Watkins
Abstract: Provided herein are immunoconjugates comprising an anti-ROR1 antibody or an antigen-fragment fragment thereof and a drug moiety. These immunoconjugates are useful for treating ROR1 expressing cancers.
Type:
Application
Filed:
April 5, 2019
Publication date:
January 30, 2020
Applicant:
VelosBio Inc.
Inventors:
Brian Lannutti, Katti Jessen, Thanh-Trang Vo, Jeffry Dean Watkins
Abstract: Provided herein are immunoconjugates comprising an anti-ROR1 antibody or an antigen-fragment fragment thereof and a drug moiety. These immunoconjugates are useful for treating ROR1 expressing cancers.
Type:
Grant
Filed:
July 5, 2018
Date of Patent:
July 2, 2019
Assignee:
VelosBio Inc.
Inventors:
Brian Lannutti, Katti Jessen, Thanh-Trang Vo, Jeffry Dean Watkins
Abstract: Provided herein are immunoconjugates comprising an anti-ROR1 antibody or an antigen-fragment fragment thereof and a drug moiety. These immunoconjugates are useful for treating ROR1 expressing cancers.
Type:
Application
Filed:
July 5, 2018
Publication date:
December 27, 2018
Applicant:
VelosBio Inc.
Inventors:
Brian Lannutti, Katti Jessen, Thanh-Trang Vo, Jeffry Dean Watkins