Patents Assigned to Vendevia Group, LLC
  • Gene silencing of the brother of the regulator of imprinted sites (BORIS)
    Patent number: 8263571
    Abstract: The present invention provides methods and compositions useful for inhibiting expression of the gene encoding the transcription factor, Brother of the Regulatory of Imprinted Sites (BORIS) by RNA interference. Methods of the present invention can be used to silence BORIS in cancer cells, which results in apoptosis and may be useful as for treating cancer in mammals. The methods of the invention directed to cancer therapy can be used alone or in combination with standard cancer treatments such as surgery, radiation, chemotherapy, and immunotherapy.
    Type: Grant
    Filed: August 11, 2008
    Date of Patent: September 11, 2012
    Assignee: Vendevia Group, LLC
    Inventors: Boris N. Reznik, Christopher J. Dougherty, Thomas Ichim
  • GENE SILENCING OF THE BROTHER OF THE REGULATOR OF IMPRINTED SITES (BORIS)
    Publication number: 20100279291
    Abstract: The present invention provides methods and compositions useful for inhibiting expression of the gene encoding the transcription factor, Brother of the Regulatory of Imprinted Sites (BORIS) by RNA interference. Methods of the present invention can be used to silence BORIS in cancer cells, which results in apoptosis and may be useful as for treating cancer in mammals. The methods of the invention directed to cancer therapy can be used alone or in combination with standard cancer treatments such as surgery, radiation, chemotherapy, and immunotherapy.
    Type: Application
    Filed: August 11, 2008
    Publication date: November 4, 2010
    Applicant: VENDEVIA GROUP, LLC
    Inventors: Boris N. Reznik, Christopher J. Dougherty, Thomas Ichim