Patents Assigned to Veracyte, Inc.
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Patent number: 11976329Abstract: The present disclosure provides systems, methods, and classifiers for differentiating between samples as usual interstitial pneumonia (UIP) or non-UIP.Type: GrantFiled: December 21, 2021Date of Patent: May 7, 2024Assignee: Veracyte, Inc.Inventors: Giulia C. Kennedy, Jing Huang, Yoonha Choi, Daniel Pankratz, Patric Sean Walsh
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Patent number: 11639527Abstract: The present invention provides methods for sequencing and analysis of nucleic acids and determining that a subject is positive for a non-usual interstitial pneumonia subtype.Type: GrantFiled: March 30, 2021Date of Patent: May 2, 2023Assignee: Veracyte, Inc.Inventors: Giulia C. Kennedy, James Diggans, Jing Huang, Yoonha Choi, Su Yeon Kim, Daniel Pankratz, Moraima Pagan
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Patent number: 11217329Abstract: The methods disclosed herein can be used to determine sample integrity, such as sample identity, by using kinship coefficients. Kinship coefficients between two samples can be determined by measuring genetic relatedness in order to determine whether the samples are related or not related.Type: GrantFiled: June 25, 2018Date of Patent: January 4, 2022Assignee: Veracyte, Inc.Inventors: Yoonha Choi, Joshua Babiarz, Giulia C. Kennedy, Jing Huang
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Patent number: 10934587Abstract: The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to genomic DNA markers associated with cancer. In particular, the present invention provides molecular profiles associated with thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.Type: GrantFiled: January 13, 2014Date of Patent: March 2, 2021Assignee: Veracyte, Inc.Inventors: Giulia Kennedy, Bonnie H. Anderson, Darya I. Chudova, Eric T. Wang, Hui Wang, Moraima Pagan, Nusrat Rabbee, Jonathan I. Wilde
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Patent number: 10731223Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.Type: GrantFiled: September 12, 2017Date of Patent: August 4, 2020Assignee: Veracyte, Inc.Inventors: Giulia C. Kennedy, Darya I. Chudova, Eric T. Wang, Jonathan I. Wilde
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Patent number: 10672504Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.Type: GrantFiled: March 14, 2019Date of Patent: June 2, 2020Assignee: Veracyte, Inc.Inventors: Giulia C. Kennedy, Darya I. Chudova, Eric T. Wang, Jonathan I. Wilde, Bonnie H. Anderson, Hui Wang, Moraima Pagan, Nusrat Rabbee
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Patent number: 10526655Abstract: The invention in some aspects provides methods of determining the likelihood that a subject has COPD based on the expression of informative-genes. In other aspects, the invention provides methods for determining an appropriate diagnostic intervention plan for a subject based on the expression of informative-genes. Related compositions and kits are provided in other aspects of the invention.Type: GrantFiled: March 13, 2014Date of Patent: January 7, 2020Assignee: Veracyte, Inc.Inventors: Duncan H. Whitney, Jun Luo
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Patent number: 10446272Abstract: Disclosed herein are kits, compositions, and methods relating to the classification of samples. Methods disclosed herein can be used to identify sample mix-ups. Methods disclosed herein can also be used to diagnose conditions or to support treatment-related decisions.Type: GrantFiled: September 12, 2017Date of Patent: October 15, 2019Assignee: Veracyte, Inc.Inventors: Jonathan I. Wilde, Darya Chudova, Giulia C. Kennedy
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Patent number: 10236078Abstract: The present disclosure provides methods for processing or analyzing a sample of tissue of a subject, to generate a classification of the sample of tissue as positive or negative for thyroid cancer. The present disclosure also provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results.Type: GrantFiled: July 27, 2017Date of Patent: March 19, 2019Assignee: Veracyte, Inc.Inventors: Giulia C. Kennedy, Darya I. Chudova, Eric T. Wang, Jonathan I. Wilde
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Patent number: 10114924Abstract: The present disorders disclosure provides method for processing or analyzing a sample of thyroid tissue of a subject, to generate a classification of the sample of thyroid tissue as positive or negative for thyroid cancer. The present disclosure also provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results, which may be used to provide a diagnosis.Type: GrantFiled: December 21, 2017Date of Patent: October 30, 2018Assignee: Veracyte, Inc.Inventors: Giulia C. Kennedy, Darya I. Chudova, Eric T. Wang, Jonathan I. Wilde, Bonnie H. Anderson, Hui Wang, Moraima Pagan, Nusrat Rabbee
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Patent number: 9495515Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.Type: GrantFiled: December 9, 2010Date of Patent: November 15, 2016Assignee: Veracyte, Inc.Inventors: Giulia C. Kennedy, Darya I. Chudova, Eric T. Wang, Jonathan I. Wilde
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Publication number: 20140378425Abstract: The present disclosure provides methods for diagnosis of interstitial lung diseases (ILDs). The present disclosure provides methods for differential diagnosis of idiopathic pulmonary fibrosis from other ILDs. Compositions and kits useful in carrying out a subject method are also provided.Type: ApplicationFiled: March 14, 2014Publication date: December 25, 2014Applicant: Veracyte, Inc.Inventors: Jonathan I. Wilde, Sharlene Velichko, Catalin Barbacioru, James Diggans, Giulia Kennedy
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Publication number: 20140349864Abstract: The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to gene expression product markers, alternative exon usage markers, and DNA polymorphisms associated with cancer. In particular, the present invention provides molecular profiles associated with thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.Type: ApplicationFiled: November 21, 2013Publication date: November 27, 2014Applicant: Veracyte, Inc.Inventors: Giulia C. Kennedy, Bonnie H. Anderson, Darya I. Chudova, Eric T. Wang, Hui Wang, Moraima Pagan, Nusrat Rabbee, Jonathan I. Wilde
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Publication number: 20140228237Abstract: The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to genomic DNA markers associated with cancer. In particular, the present invention provides molecular profiles associated with thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.Type: ApplicationFiled: January 13, 2014Publication date: August 14, 2014Applicant: Veracyte, Inc.Inventors: Giulia Kennedy, Bonnie H. Anderson, Darya I. Chudova, Eric T. Wang, Hui Wang, Moraima Pagan, Nusrat Rabbee, Jonathan I. Wilde
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Patent number: 8669057Abstract: The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to genomic DNA markers associated with cancer. In particular, the present invention provides molecular profiles associated with thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.Type: GrantFiled: May 7, 2010Date of Patent: March 11, 2014Assignee: Veracyte, Inc.Inventors: Giulia C. Kennedy, Bonnie H. Anderson, Darya I. Chudova, Eric T. Wang, Hui Wang, Moraima Pagan, Nusrat Rabbee, Jonathan I. Wilde
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Patent number: 8541170Abstract: The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to gene expression product markers, alternative exon usage markers, and DNA polymorphisms associated with cancer. In particular, the present invention provides molecular profiles associated with thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.Type: GrantFiled: November 17, 2009Date of Patent: September 24, 2013Assignee: Veracyte, Inc.Inventors: Giulia C. Kennedy, Bonnie H. Anderson, Darya I. Chudova, Eric T. Wang, Hui Wang, Moraima Pagan, Nusrat Rabbee, Jonathan I. Wilde
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Publication number: 20130225662Abstract: The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to gene expression product markers, alternative exon usage markers, and DNA polymorphisms associated with cancer. In particular, the present invention provides molecular profiles associated with thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.Type: ApplicationFiled: August 17, 2012Publication date: August 29, 2013Applicant: Veracyte, Inc.Inventors: Giulia C. Kennedy, Bonnie H. Anderson, Darya I. Chudova, Eric T. Wang, Hui Wang, Moraima Pagan, Nusrat Rabbee, Jonathan I. Wilde
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Publication number: 20130150257Abstract: Compositions and methods are provided to provide an expression signature for a sample, where an alternative splicing index and profile are determined for the sample based on variations in the splicing of messenger RNA for at least one gene in the sample.Type: ApplicationFiled: December 10, 2012Publication date: June 13, 2013Applicant: Veracyte, Inc.Inventor: Veracyte, Inc.
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Publication number: 20120220474Abstract: The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to genomic DNA markers associated with cancer. In particular, the present invention provides molecular profiles associated with thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.Type: ApplicationFiled: May 7, 2010Publication date: August 30, 2012Applicant: Veracyte, Inc.Inventors: Giulia C. Kennedy, Bonnie H. Anderson, Darya I. Chudova, Eric T. Wang, Hui Wang, Moraima Pagan, Nusrat Rabbee, Jonathan I. Wilde
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Publication number: 20110312520Abstract: The present invention relates to compositions, kits, and methods for molecular profiling for diagnosing disease conditions. In particular, the present invention provides molecular profiles associated with thyroid cancer and other cancers, methods of relating molecular profiles to a diagnosis, and related compositions.Type: ApplicationFiled: May 11, 2011Publication date: December 22, 2011Applicant: Veracyte, Inc.Inventors: Giulia C. Kennedy, Darya I. Chudova, Jonathan I. Wilde, James G. Veitch, Bonnie H. Anderson