Patents Assigned to Verastem
  • PYRIMIDINE SUBSTITUTED PURINE DERIVATIVES
    Publication number: 20130079512
    Abstract: The present invention relates to purine compounds that are useful as kinase inhibitors. More particularly, the present invention relates to purine compounds, methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment of proliferative conditions or disorders. These compounds may be useful as medicaments for the treatment of a number of proliferative conditions or disorders including tumours and cancers as well as other disorders or conditions related to or associated with PI3 and/or mTOR kinases.
    Type: Application
    Filed: July 20, 2012
    Publication date: March 28, 2013
    Applicant: Verastem
    Inventors: Harish K. Nagaraj, Meredith Williams
  • Pyrimidine substituted purine derivatives
    Patent number: 8247410
    Abstract: The present invention relates to purine compounds that are useful as kinase inhibitors. More particularly, the present invention relates to purine compounds, methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment of proliferative conditions or disorders. These compounds may be useful as medicaments for the treatment of a number of proliferative conditions or disorders including tumors and cancers as well as other disorders or conditions related to or associated with PI3 and/or mTOR kinases.
    Type: Grant
    Filed: October 3, 2008
    Date of Patent: August 21, 2012
    Assignee: Verastem
    Inventors: Harish K. Nagaraj, Meredith Williams