Patents Assigned to Verge Analytics, Inc.
  • Substituted Pyrazolo-Pyrimidines and Uses Thereof
    Publication number: 20260053813
    Abstract: The present disclosure provides modified forms, or prodrugs, of therapeutic agents or compounds that are inhibitors of PIKfyve kinases useful for the treatment of neurological diseases treatable by inhibition of PIKfyve. Also provided are pharmaceutical compositions containing such prodrug compounds, and methods of treatment using such compounds.
    Type: Application
    Filed: February 7, 2024
    Publication date: February 26, 2026
    Applicant: Verge Analytics, Inc.
    Inventors: Robert A. Galemmo, Jr., Brian C. Shook, Weiling Liang, Irene Y. Choi-Muckerheide, Brian Kopec
  • Substituted pyrazolo-pyrimidines and uses thereof
    Patent number: 12486274
    Abstract: The present disclosure provides compounds that are inhibitors of PIKfyve kinases useful for the treatment of neurological diseases treatable by inhibition of PIKfyve. Also provided are pharmaceutical compositions containing such compounds, and methods of treatment using such compounds.
    Type: Grant
    Filed: January 12, 2021
    Date of Patent: December 2, 2025
    Assignee: Verge Analytics, Inc.
    Inventors: Mark D. Rosen, Robert A. Galemmo, Jr., Weiling Liang, Brian Kopec, Irene Y. Choi-Muckerheide, Jane Rhodes
  • Substituted Pyrimidines and Uses Thereof
    Publication number: 20230146395
    Abstract: The present disclosure provides compounds that are inhibitors of PIKfyve and/or PI3 kinases, and are therefore useful for the treatment of neurological diseases treatable by inhibition of PIKfyve and/or PI3 kinases. Also provided are pharmaceutical compositions containing such compounds, and methods of treatment of neurological diseases using such compounds.
    Type: Application
    Filed: March 8, 2021
    Publication date: May 11, 2023
    Applicant: Verge Analytics, Inc.
    Inventors: Mark D. Rosen, Robert A. Galemmo, Jr., Weiling Liang, Irene Y. Choi, Brian Kopec, Jane Rhodes
  • Substituted Pyrazolo-Pyrimidines and Uses Thereof
    Publication number: 20230133203
    Abstract: The present disclosure provides compounds that are inhibitors of PIKfyve kinases useful for the treatment of neurological diseases treatable by inhibition of PIKfyve. Also provided are pharmaceutical compositions containing such compounds, and methods of treatment using such compounds.
    Type: Application
    Filed: January 12, 2021
    Publication date: May 4, 2023
    Applicant: Verge Analytics, Inc.
    Inventors: Mark D. Rosen, Robert A. Galemmo, JR., Weiling Liang, Brian Kopec, Irene Y. Choi, Jane Rhodes
  • Fused Tricyclic Heterocyclic Compounds and Uses Thereof
    Publication number: 20230038929
    Abstract: The present disclosure provides compounds that are inhibitors of PIKfyve and/or PI3 kinases, and are therefore useful for the treatment of neurological diseases that are treatable by inhibition of PIKfyve. Also provided are pharmaceutical compositions containing such compounds, and methods of treatment using such compounds.
    Type: Application
    Filed: December 4, 2020
    Publication date: February 9, 2023
    Applicant: Verge Analytics, Inc.
    Inventors: Mark D. Rosen, Robert A. Galemmo, JR., William J. Guilford, Weiling Liang, Irene Y. Choi, Bryan Kopek, Jane Rhodes