Patents Assigned to Verigen, Inc.
  • Active induction or passive immunization of anti-Gp48 antibodies and isolated gp48 protein
    Patent number: 5830476
    Abstract: The instant invention provides for isolated gp48 glycoprotein, methods of passive immunization with anti-gp48 antibodies, and methods of active immunization for generating anti-gp48 antibodies.
    Type: Grant
    Filed: September 15, 1994
    Date of Patent: November 3, 1998
    Assignee: Verigen, Inc.
    Inventors: Kurt B. Osther, Chung-Ho Hung
  • Anti-HIV-1 neutralizing antibodies
    Patent number: 5658569
    Abstract: The disclosure relates to antibodies reactive with HIV-1 antigens and the use of such antibodies in vaccine preparations, immunotherapeutic preparations and assays for HIV-1.
    Type: Grant
    Filed: May 23, 1994
    Date of Patent: August 19, 1997
    Assignee: Verigen, Inc.
    Inventors: Kurt B. Osther, Gottfried H. Kellermann
  • Anti-HIV-1 neutralizing antibodies
    Patent number: 5529776
    Abstract: The disclosure relates to antibodies reactive with HIV-1 antigens and the use of such antibodies in vaccine preparations, immunotherapeutic preparations and assays for HIV-1.
    Type: Grant
    Filed: December 27, 1993
    Date of Patent: June 25, 1996
    Assignee: Verigen Inc.
    Inventors: Kurt B. Osther, Gottfried H. Kellermann
  • Antibodies specific towards gp 48
    Patent number: 5516895
    Abstract: Monoclonal and polyclonal antibodies specific towards, gp 48, having a molecular weight ranging from 46 kDa to 53 kDa. The gp 48 antibodies bind to the CD4 receptors on T4 lymphocytes, inhibiting if not neutralizing the HIV-1 virus from reacting therewith. Anti-gp 48 can be used for treating and diagnosing AIDS and related diseases.
    Type: Grant
    Filed: February 14, 1994
    Date of Patent: May 14, 1996
    Assignee: Verigen, Inc.
    Inventor: Kurt B. Osther
  • Antibodies specific towards HIV-1 gp 48
    Patent number: 5286852
    Abstract: Monoclonal and polyclonal antibodies specific towards, gp 48, having a molecular weight ranging from 46 kDa to 53 kDa. The gp 48 antibodies bind to the CD4 receptors on T4 lymphocytes, inhibiting if not neutralizing the HIV-1 virus from reacting therewith. Anti-gp 48 can be used for diagnosing AIDS and related diseases.
    Type: Grant
    Filed: October 8, 1991
    Date of Patent: February 15, 1994
    Assignee: Verigen, Inc.
    Inventor: Kurt B. Osther
  • Method for determining the sensitivity and/or specificity of an assay system for detecting antibodies
    Patent number: 5264342
    Abstract: A method for determining the sensitivity and/or specificity of assays that detect the presence or absence of antibodies to viral and/or other microbial infective agents using porcine seroconversion panels, and production of the seroconversion panels is provided.
    Type: Grant
    Filed: October 16, 1992
    Date of Patent: November 23, 1993
    Assignee: Verigen, Inc.
    Inventors: Kurt B. Osther, Gottfried H. Kellermann
  • Method for rapid and sensitive detection of IgM retroviral antibodies
    Patent number: 5093230
    Abstract: A rapid and sensitive assay method for the detection of IgM antibody or the simultaneous detection of IgG and IgM antibody to retroviruses, including HIV-1 and HIV-2, and diagnostic test kits for carrying out the method is provided. According to the method of the invention, results are obtainable within 70 minutes.
    Type: Grant
    Filed: May 5, 1989
    Date of Patent: March 3, 1992
    Assignee: Verigen, Inc.
    Inventors: Kurt B. Osther, Louis M. Dyll