Patents Assigned to Vermillion, Inc.
  • PREDICTIVE BIOMARKERS FOR OVARIAN CANCER
    Publication number: 20200256874
    Abstract: Methods are provided for predicting the presence, subtype and stage of ovarian cancer, as well as for assessing the therapeutic efficacy of a cancer treatment and determining whether a subject potentially is developing cancer. Associated test kits, computer and analytical systems as well as software and diagnostic models are also provided.
    Type: Application
    Filed: February 18, 2020
    Publication date: August 13, 2020
    Applicant: VERMILLION, INC.
    Inventors: BRIAN C. MANSFIELD, PING F. YIP, SURAJ AMONKAR, GREG P. BERTENSHAW
  • Predictive biomarkers for ovarian cancer
    Patent number: 10605811
    Abstract: Methods are provided for predicting the presence, subtype and stage of ovarian cancer, as well as for assessing the therapeutic efficacy of a cancer treatment and determining whether a subject potentially is developing cancer. Associated test kits, computer and analytical systems as well as software and diagnostic models are also provided.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: March 31, 2020
    Assignee: VERMILLION, INC.
    Inventors: Brian C. Mansfield, Ping F. Yip, Suraj Amonkar, Greg P. Bertenshaw
  • BIOMARKERS FOR OVARIAN CANCER CTAP3-RELATED PROTEINS
    Publication number: 20180196054
    Abstract: The present invention provides a protein-based biomarker that is useful qualifying ovarian cancer status to a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.
    Type: Application
    Filed: November 10, 2017
    Publication date: July 12, 2018
    Applicants: VERMILLION, INC., THE JOHNS HOPKINS UNIVERSITY
    Inventors: ZHEN ZHANG, DANIEL W. CHAN, ERIC T. FUNG, ZHENG WANG, FUJUN ZHANG
  • Predictive biomarkers for ovarian cancer
    Patent number: 9846158
    Abstract: Methods are provided for predicting the presence, subtype and stage of ovarian cancer, as well as for assessing the therapeutic efficacy of a cancer treatment and determining whether a subject potentially is developing cancer. Associated test kits, computer and analytical systems as well as software and diagnostic models are also provided.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: December 19, 2017
    Assignee: Vermillion, Inc.
    Inventors: Brian C. Mansfield, Ping F. Yip, Suraj Amonkar, Greg P. Bertenshaw
  • Biomarker for ovarian cancer CTAP3-related proteins
    Patent number: 9816995
    Abstract: The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: November 14, 2017
    Assignees: Vermillion, Inc., The Johns Hopkins University
    Inventors: Zhen Zhang, Daniel W. Chan, Eric T. Fung, Zheng Wang, Fujun Zhang
  • BIOMARKERS FOR OVARIAN CANCER
    Publication number: 20170089906
    Abstract: The present invention provides protein-based biomarkers and biomarker combinations that am useful in qualifying ovarian cancer status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as ovarian cancer, ovarian cancer of low malignant potential, benign ovarian disease or other malignant condition. The biomarkers can be detected by SELDI mass spectrometry.
    Type: Application
    Filed: November 30, 2016
    Publication date: March 30, 2017
    Applicants: VERMILLION, INC., THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION
    Inventors: ERIC THOMAS FUNG, FREDERICK RAND UELAND, J.R. VAN NAGELL, PAUL DUANE DEPRIEST, ANDRE THOMAS BARON
  • PREDICTIVE BIOMARKERS FOR OVARIAN CANCER
    Publication number: 20160245818
    Abstract: Methods are provided for predicting the presence, subtype and stage of ovarian cancer, as well as for assessing the therapeutic efficacy of a cancer treatment and determining whether a subject potentially is developing cancer. Associated test kits, computer and analytical systems as well as software and diagnostic models are also provided.
    Type: Application
    Filed: February 11, 2016
    Publication date: August 25, 2016
    Applicant: VERMILLION, INC.
    Inventors: BRIAN C. MANSFIELD, PING F. YIP, SURAJ AMONKAR, GREG P. BERTENSHAW
  • COMPOSITIONS FOR OVARIAN CANCER ASSESSMENT HAVING IMPROVED SPECIFICTY
    Publication number: 20160109455
    Abstract: The present invention provides compositions and methods that provide a high degree of sensitivity and a high degree of specificity for the preoperative assessment of ovarian tumors in a variety of subject's (e.g., pre- and post-menopausal women) having a variety of ovarian cancer types (e.g., clear cell/mucinous, low malignant potential, high malignant potential) and at a variety of disease states (e.g., early and late stage).
    Type: Application
    Filed: May 8, 2014
    Publication date: April 21, 2016
    Applicants: VERMILLION, INC., THE JOHNS HOPKINS UNIVERSITY
    Inventors: DONALD MUNROE, DANIEL W. CHAN, ZHEN ZHANG
  • Predictive markers for ovarian cancer
    Patent number: 9274118
    Abstract: Methods are provided for predicting the presence, subtype and stage of ovarian cancer, as well as for assessing the therapeutic efficacy of a cancer treatment and determining whether a subject potentially is developing cancer. Associated test kits, computer and analytical systems as well as software and diagnostic models are also provided.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: March 1, 2016
    Assignee: Vermillion, Inc.
    Inventors: Brian C. Mansfield, Ping F. Yip, Suraj Amonkar, Greg P. Bertenshaw
  • BIOMARKERS FOR OVARIAN CANCER: Beta 2 MICROGLOBULIN
    Publication number: 20150153348
    Abstract: The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.
    Type: Application
    Filed: December 4, 2013
    Publication date: June 4, 2015
    Applicant: Vermillion, Inc.
    Inventors: Eric T. Fung, Enrique Dalmasso, Valdimir Podust, Zheng Wang
  • Prognostic Biomarkers in Patients with Ovarian Cancer
    Publication number: 20150126384
    Abstract: The present invention provides methods for assessing an ovarian cancer patient's survival status. Also, methods for evaluating the ovarian cancer state of a patient are described herein. These methods involve the detection, analysis, and classification of biological patterns in biological samples. The biological patterns are obtained using, for example, mass spectrometry systems and other techniques.
    Type: Application
    Filed: November 6, 2013
    Publication date: May 7, 2015
    Applicant: VERMILLION, INC.
    Inventors: Estrid Hogdall, Eric T. Fung, Jarle IB Christensen, Claus Hogdall
  • BIOMARKER PANELS, DIAGNOSTIC METHODS AND TEST KITS FOR OVARIAN CANCER
    Publication number: 20150031561
    Abstract: Methods are provided for predicting the presence, subtype and stage of ovarian cancer, as well as for assessing the therapeutic efficacy of a cancer treatment and determining whether a subject potentially is developing cancer. Associated test kits, computer and analytical systems as well as software and diagnostic models are also provided.
    Type: Application
    Filed: December 6, 2013
    Publication date: January 29, 2015
    Applicant: Vermillion, Inc.
    Inventors: Greg P. Bertenshaw, Ping F. Yip, Partha Seshaiah
  • BIOMARKER FOR OVARIAN CANCER CTAP3-RELATED PROTEINS
    Publication number: 20140274787
    Abstract: The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 18, 2014
    Applicants: Vermillion, Inc., The Johns Hopkins University
    Inventors: ZHEN ZHANG, DANIEL W. CHAN, ERIC T. FUNG, ZHENG WANG, FUJUN ZHANG
  • PREDICTIVE MARKERS FOR OVARIAN CANCER
    Publication number: 20140221240
    Abstract: Methods are provided for predicting the presence, subtype and stage of ovarian cancer, as well as for assessing the therapeutic efficacy of a cancer treatment and determining whether a subject potentially is developing cancer. Associated test kits, computer and analytical systems as well as software and diagnostic models are also provided.
    Type: Application
    Filed: February 4, 2014
    Publication date: August 7, 2014
    Applicant: Vermillion, Inc.
    Inventors: Brian C. Mansfield, Ping F. Yip, Suraj Amonkar, Greg P. Bertenshaw
  • ?-2 microglobulin as a biomarker for peripheral artery disease
    Patent number: 8709735
    Abstract: The present invention provides ?2 microglobulin as a biomarker for qualifying or assessing peripheral artery disease in a subject.
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: April 29, 2014
    Assignees: Vermillion, Inc., Board of Trustees of of the Leland Stanford Junior University
    Inventors: John P. Cooke, Eric T. Fung, Elichiro Kimura
  • Biomarkers for ovarian cancer
    Patent number: 8682591
    Abstract: The present invention relates to a method of qualifying ovarian cancer status in a subject comprising: (a) measuring at least one biomarker in a sample from the subject and (b) correlating the measurement with ovarian cancer status. The invention further relates to kits for qualifying ovarian cancer status in a subject.
    Type: Grant
    Filed: February 13, 2012
    Date of Patent: March 25, 2014
    Assignees: Vermillion, Inc., The Johns Hopkins University
    Inventors: Daniel W. Chan, Zhen Zhang, Eric Fung, Xiao-Ying Meng
  • Predictive markers for ovarian cancer
    Patent number: 8664358
    Abstract: Methods are provided for predicting the presence, subtype and stage of ovarian cancer, as well as for assessing the therapeutic efficacy of a cancer treatment and determining whether a subject potentially is developing cancer. Associated test kits, computer and analytical systems as well as software and diagnostic models are also provided.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: March 4, 2014
    Assignee: Vermillion, Inc.
    Inventors: Brian C. Mansfield, Ping F. Yip, Suraj Amonkar, Greg P. Bertenshaw
  • BIOMARKERS FOR OVARIAN CANCER
    Publication number: 20140038899
    Abstract: The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as ovarian cancer, ovarian cancer of low malignant potential, benign ovarian disease or other malignant condition. The biomarkers can be detected by SELDI mass spectrometry.
    Type: Application
    Filed: June 12, 2013
    Publication date: February 6, 2014
    Applicants: The University of Kentucky Research Foundation, Vermillion, Inc.
    Inventors: Eric Thomas Fung, Frederick Rand Ueland, Van Nagell, JR., Paul Duane Depriest, Andre Thomas Baron
  • USE OF BIOMARKERS FOR DETECTING OVARIAN CANCER
    Publication number: 20140038852
    Abstract: The present invention relates to a method of qualifying ovarian cancer status in a subject comprising: (a) measuring at least one biomarker in a sample from the subject and (b) correlating the measurement with ovarian cancer status. The invention further relates to kits for qualifying ovarian cancer status in a subject.
    Type: Application
    Filed: May 20, 2013
    Publication date: February 6, 2014
    Applicants: Vermillion, Inc., The Johns Hopkins University
    Inventors: The Johns Hopkins University, Vermillion, Inc.
  • BIOMARKERS FOR THE DETECTION OF EARLY STAGE OVARIAN CANCER
    Publication number: 20140038837
    Abstract: The present invention provides methods and compositions for detecting early stage ovarian cancer in a patient. Also, methods for evaluating the ovarian cancer state of a patient are described herein. These methods involve the detection, analysis, and classification of biomarkers in biological samples.
    Type: Application
    Filed: June 3, 2013
    Publication date: February 6, 2014
    Applicants: Board of Regents, The University of Texas System, Vermillion, Inc.
    Inventors: Eric Thomas Fung, Charlotte Clarke, Robert Bast, Kevin Coombes