Patents Assigned to VERSEON CORPORATION
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Patent number: 10653674Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.Type: GrantFiled: March 27, 2018Date of Patent: May 19, 2020Assignee: VERSEON CORPORATIONInventors: Kevin Michael Short, Son Minh Pham, David Charles Williams, Somalee Datta
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Patent number: 10532995Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin and/or kallikrein, which compounds include substituted pyrazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which diseases or disorders are amenable to treatment or prevention by the inhibition of thrombin and/or kallikrein.Type: GrantFiled: February 29, 2016Date of Patent: January 14, 2020Assignee: VERSEON CORPORATIONInventors: Kevin Michael Short, Maria de los Angeles Estiarte-Martinez, David Ben Kita, Timothy Philip Shiau
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Patent number: 10251872Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.Type: GrantFiled: November 13, 2017Date of Patent: April 9, 2019Assignee: VERSEON CORPORATIONInventors: Kevin Michael Short, Son Minh Pham, David Charles Williams, David Ben Kita
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Patent number: 10189810Abstract: There are provided inter alia pyrazolyl-substituted pyridone compounds, which exhibit biological activity, e.g., inhibitory action, against serine proteases, including thrombin and various kallikreins. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of serine proteases, including thrombin and various kallikreins.Type: GrantFiled: September 17, 2015Date of Patent: January 29, 2019Assignee: VERSEON CORPORATIONInventors: Kevin Michael Short, David Ben Kita, Maria de los Angeles Estiarte-Martinez, Son Minh Pham
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Patent number: 10058541Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.Type: GrantFiled: May 25, 2017Date of Patent: August 28, 2018Assignee: VERSEON CORPORATIONInventors: Kevin Michael Short, Son Minh Pham, David Charles Williams, David Ben Kita
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Patent number: 9963440Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.Type: GrantFiled: January 22, 2016Date of Patent: May 8, 2018Assignee: VERSEON CORPORATIONInventors: Kevin Michael Short, Son Minh Pham, David Charles Williams, Somalee Datta
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Patent number: 9951025Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.Type: GrantFiled: March 17, 2014Date of Patent: April 24, 2018Assignee: VERSEON CORPORATIONInventors: Kevin Michael Short, Son Minh Pham, David Charles Williams
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Patent number: 9687479Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.Type: GrantFiled: November 17, 2016Date of Patent: June 27, 2017Assignee: VERSEON CORPORATIONInventors: Kevin Michael Short, Son Minh Pham, David Charles Williams, David Ben Kita
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Patent number: 9533970Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.Type: GrantFiled: March 17, 2014Date of Patent: January 3, 2017Assignee: VERSEON CORPORATIONInventors: Kevin Michael Short, Son Minh Pham, David Charles Williams, David Ben Kita
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Patent number: 9533967Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.Type: GrantFiled: September 28, 2012Date of Patent: January 3, 2017Assignee: VERSEON CORPORATIONInventors: Kevin Michael Short, Son Minh Pham, David Charles Williams, Somalee Datta
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Patent number: 9317664Abstract: A method for partitioning a molecular subset is described. The partitioning method takes into account molecular structure and its manner of storage and transmission, transformations to be applied to the molecular subset and their implementation, and constraints imposed by the implementation of the partitioning method. Using this method, a molecular subset can be stored, transmitted, and processed more efficiently. The resulting efficiency makes it possible to design and run applications which require complex molecular processing, such as rational drug discovery, virtual library design, etc.Type: GrantFiled: October 14, 2004Date of Patent: April 19, 2016Assignee: VERSEON CORPORATIONInventors: Sachin Ahuja, David Kita, Eniko Fodor, Adityo Prakash
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Publication number: 20130040950Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.Type: ApplicationFiled: September 28, 2012Publication date: February 14, 2013Applicant: VERSEON CORPORATIONInventor: VERSEON CORPORATION