Abstract: The invention includes a tetrapeptide to be used in the treatment of Alzheimer's disease and depression. The tetrapeptide comprises the general formula, acetyl-X-ARG-ARG-amide, where X=-(D-ARG)-ARG-; -(D-LYS)-LYS-; or -(D-MET)-MET-. On the basis of the combination of pharmacological properties identified, a preparation including the tetrapeptide has potential for clinical use as a nootropic, neuroprotective, and antidepressant agent.
Type:
Grant
Filed:
January 29, 2018
Date of Patent:
November 24, 2020
Assignee:
“VERTA RESEARCH-PRODUCTION COMPANY”LTD
Inventors:
Roman Danilovich Dejko, Alexandr Alexandrovich Kolobov, Elena Arturovna Kampe-Nemm, Vladimir Michajlovich Shpen