Patents Assigned to Verus Pharmaceuticals, Inc.
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Publication number: 20080020003Abstract: The present invention relates to method for inducing bronchodilation in a patient in need thereof comprising (a) providing at least one dose of an inhalation mixture comprising a ?2 agonist to said patient; and (b) delivering said inhalation mixture with an inhalation nebulizer, as well as dosage formulations comprising a ?2 agonist.Type: ApplicationFiled: May 18, 2007Publication date: January 24, 2008Applicant: Verus Pharmaceuticals, Inc.Inventors: Malcolm Hill, Hemant Deshmukh, Elaine Phillips
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Publication number: 20070276048Abstract: The present invention relates to unit dose formulations comprising an inhalable albuterol solution, wherein the inhalation albuterol solution is formulated with albuterol free base, a tonicity adjusting agent, a pH adjusting agent and water. Methods of preparing the unit dose formulation are also provided.Type: ApplicationFiled: May 18, 2007Publication date: November 29, 2007Applicant: Verus Pharmaceuticals, Inc.Inventors: Hemant Deshmukh, Elaine Phillips, Malcolm Hill
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Publication number: 20070249572Abstract: The present invention relates to methods and systems for the delivery of a corticosteroid comprising (1) an inhalable aqueous mixture comprising a corticosteroid and a solubility enhancer and (2) an inhalable nebulizer, wherein the delivery of the aqueous mixture comprising the corticosteroid by the nebulizer results in an enhanced pharmacokinetic profile of the corticosteroid as compared to conventional inhalable therapies and/or increase lung deposition.Type: ApplicationFiled: December 20, 2006Publication date: October 25, 2007Applicant: Verus Pharmaceuticals, Inc.Inventor: Malcolm Hill
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Publication number: 20070219498Abstract: An automatic injector comprising an improved energy management system as well as an improved shock absorber system adapted to reduce dynamic stresses on internal device components is provided. In particular, a shock absorber system comprising a stationary shock absorber is provided. In some embodiments, the stationary shock absorber is located in the nose of the automatic injector.Type: ApplicationFiled: February 28, 2007Publication date: September 20, 2007Applicant: Verus Pharmaceuticals, Inc.Inventors: Greg Malone, Eric Warner
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Publication number: 20070197486Abstract: The present invention relates to methods and systems for the delivery of a corticosteroid comprising (1) an inhalable aqueous mixture comprising a corticosteroid and a solubility enhancer and (2) an inhalable nebulizer, wherein the delivery of the aqueous mixture comprising the corticosteroid by the nebulizer results in an enhanced pharmacokinetic profile of the corticosteroid as compared to conventional inhalable therapies and/or increase lung deposition.Type: ApplicationFiled: December 19, 2006Publication date: August 23, 2007Applicant: Verus Pharmaceuticals, Inc.Inventor: Malcolm Hill
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Publication number: 20070197487Abstract: The present invention relates to methods and systems for the delivery of a corticosteroid comprising (1) an inhalable aqueous mixture comprising a corticosteroid and a solubility enhancer and (2) an inhalable nebulizer, wherein the delivery of the aqueous mixture comprising the corticosteroid by the nebulizer results in an enhanced pharmacokinetic profile of the corticosteroid as compared to conventional inhalable therapies.Type: ApplicationFiled: December 19, 2006Publication date: August 23, 2007Applicant: Verus Pharmaceuticals, Inc.Inventor: Malcolm Hill
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Publication number: 20070191599Abstract: The present invention relates to methods of manufacturing compositions comprising a corticosteriod and at least one solubility enhancer, as well as compositions made by these methods.Type: ApplicationFiled: February 15, 2007Publication date: August 16, 2007Applicant: VERUS PHARMACEUTICALS, INC.Inventors: Malcolm Hill, Cynthia LiCalsi, Troy Christensen
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Publication number: 20070191327Abstract: Novel methods of sterilizing corticosteroid solutions resulting in improved final yield of active corticosteroid ingredient.Type: ApplicationFiled: February 15, 2007Publication date: August 16, 2007Applicant: VERUS PHARMACEUTICALS, INC.Inventors: Malcolm Hill, Cynthia LiCalsi
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Publication number: 20070191323Abstract: A corticosteroid mixture, such as a budesonide solution, is prepared by the active and inactive ingredients of the mixture under oxygen-depleted conditions. The resulting mixture demonstrates superior stability of the active pharmaceutical ingredient corticosteroid. The invention provides novel methods of manufacturing corticosteroid mixtures, wherein the resulting mixtures possess superior stability as compared to known methods.Type: ApplicationFiled: February 15, 2007Publication date: August 16, 2007Applicant: VERUS PHARMACEUTICALS, INC.Inventors: Malcolm Hill, Cynthia LiCalsi
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Publication number: 20070185066Abstract: The present invention relates to methods and systems for the delivery of a corticosteroid comprising (1) an inhalable aqueous mixture comprising a corticosteroid and a solubility enhancer and (2) an inhalable nebulizer, wherein the delivery of the aqueous mixture comprising the corticosteroid by the nebulizer results in an enhanced pharmacokinetic profile of the corticosteroid as compared to conventional inhalable therapies and/or increase lung deposition.Type: ApplicationFiled: December 19, 2006Publication date: August 9, 2007Applicant: Verus Pharmaceuticals, Inc.Inventor: Malcolm Hill
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Publication number: 20070178049Abstract: The present invention relates to methods and systems for the delivery of a corticosteroid comprising (1) an inhalable aqueous mixture comprising a corticosteroid and a solubility enhancer and (2) an inhalable nebulizer, wherein the delivery of the aqueous mixture comprising the corticosteroid by the nebulizer results in an enhanced pharmacokinetic profile of the corticosteroid as compared to conventional inhalable therapies, and/or increased lung deposition.Type: ApplicationFiled: December 19, 2006Publication date: August 2, 2007Applicant: Verus Pharmaceuticals, Inc.Inventor: Malcolm Hill
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Publication number: 20070178050Abstract: The present invention relates to methods and systems for the delivery of a corticosteroid comprising (1) an inhalable aqueous mixture comprising a corticosteroid and a solubility enhancer and (2) an inhalable nebulizer, wherein the delivery of the aqueous mixture comprising the corticosteroid by the nebulizer results in an enhanced pharmacokinetic profile of the corticosteroid as compared to conventional inhalable therapies.Type: ApplicationFiled: December 19, 2006Publication date: August 2, 2007Applicant: Verus Pharmaceuticals, Inc.Inventor: Malcolm Hill
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Publication number: 20070160542Abstract: The present invention relates to methods and systems for the delivery of a corticosteroid comprising (1) an inhalable aqueous mixture comprising a corticosteroid and a solubility enhancer and (2) an inhalable nebulizer, wherein the delivery of the aqueous mixture comprising the corticosteroid by the nebulizer results in an enhanced pharmacokinetic profile of the corticosteroid as compared to conventional inhalable therapies and/or increased lung deposition.Type: ApplicationFiled: December 19, 2006Publication date: July 12, 2007Applicant: Verus Pharmaceuticals, Inc.Inventor: Malcolm Hill