Abstract: An aqueous composition including torasemide and at least one organic solvent, to a bottle or container including the composition, and to a kit including the bottle or container and a device for delivery of the composition (for example a syringe). A use of at least one organic solvent for increasing the stability and/or the antimicrobial properties of a composition including torasemide. A method for preparing the composition.
Abstract: An auricular cleaning composition includes isopropylic alcohol and/or diethylene glycol monoethyl ether as ceruminolytic agent(s), optionally in combination with caprylocaproyl polyoxyl-8 glyceride.
Abstract: An auricular cleaning composition includes isopropylic alcohol and/or diethylene glycol monoethyl ether as ceruminolytic agent(s), optionally in combination with caprylocaproyl polyoxyl-8 glyceride.
Abstract: A subject of the invention is the compounds of formula (I): wherein R1, R2, R3, R?3, R4, R?4, R5, R6 and R7 are as described in the application, in the form of enantiomers or mixtures, as well as their salts with acids and bases, their preparation and their application as anti-bacterials, in both human and veterinary medicine.
Type:
Grant
Filed:
June 23, 2009
Date of Patent:
December 6, 2011
Assignee:
Vetoquinol SA
Inventors:
Sandrine Ropp, Christophe Morice, Bruno Giethlen, Paola Ciapetti, Florence Chery-Mozziconacci, Camille G. Wermuth, Francoise Leblanc, Marc Schneider
Abstract: A subject of the invention is the compounds of formula (I): in which either R1 represents H, OH, NH2, —(CH2)m—NRaRb(m=0.1 or 2), Ra and Rb represent H, linear, branched or cyclic (C1-C6) alkyl, (C3-C6) cycloalkyl-(C3-C6)— alkyl, Rc, S(O)2Rc, C(O)Rc, S(O)2Rd or C(O)Rd; or Ra and Rb with N form an Rc radical; Rc represents a saturated, unsaturated or 5- or 6-members aromatic ring, containing 1 to 4 heteroatoms chosen from N, O and S, optionally substituted; Rd represents a linear, branched or cyclic (C1-C6) alkyl, optionally substituted by 1 to 4 halogens; or R1 represents Rc or CHReRc or CHReRd; Re represents H, OH, NH2, NH—(C1-C6)-alk or N-(C1-C6)-alk2, or NH—(C1-C7)-acyl or NHRc; R2 represents H, (CH2)m—NRaRb, Rc, CHReRc or CHReRd, and R?2 represents H.
Type:
Grant
Filed:
February 27, 2009
Date of Patent:
May 11, 2010
Assignee:
Vetoquinol SA
Inventors:
Paola Ciapetti, Florence Chery-Mozziconacci, Camille G. Wermuth, Françoise Leblanc, Marc Schneider, Sandrine Ropp, Christophe Morice, Bruno Giethlen
Abstract: A subject of the invention is the compounds of formula (I): wherein R1, R2, R3, R?3, R4, R?4, R5, R6 and R7 are as described in the application, in the form of enantiomers or mixtures, as well as their salts with acids and bases, their preparation and their application as anti-bacterials, in both human and veterinary medicine.
Type:
Application
Filed:
June 23, 2009
Publication date:
January 14, 2010
Applicant:
Vetoquinol SA
Inventors:
Sandrine Ropp, Christophe Morice, Bruno Giethlen, Paola Ciapetti, Florence Chery-Mozziconacci, Camille G. Wermuth, Francoise Leblanc, Marc Schneider