Abstract: The method of treating patients by administering N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea for treatment of leukotriene related pathologies and compositions for this use.
Type:
Application
Filed:
February 10, 2011
Publication date:
February 2, 2012
Applicant:
VIA Pharmaceuticals, Inc.
Inventors:
Rebecca Taub, Tilmann Brotz, John Franc, Larry Cohen, Hemantkumar H. Patel, Sanjay R. Chemburkar, David P. Sawick
Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
Type:
Grant
Filed:
May 1, 2008
Date of Patent:
November 15, 2011
Assignee:
VIA Pharmaceuticals, Inc.
Inventors:
David Robert Bolin, Adrian Wai-Hing Cheung, Fariborz Firooznia, Matthew Michael Hamilton, Lee Apostle McDermott, Yimin Qian, Jenny Tan, Weiya Yun
Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
Type:
Grant
Filed:
November 17, 2006
Date of Patent:
May 11, 2010
Assignee:
Via Pharmaceuticals, Inc.
Inventors:
David Robert Bolin, Adrian Wai-Hing Cheung, Fariborz Firooznia, Matthew Michael Hamilton, Shiming Li, Lee Apostle McDermott, Yimin Qian, Weiya Yun
Abstract: The method of treating patients be administering phenylalkyl N-hydroxurea derivatives for combating atherosclerotic plaque and cardiovascular diseases and compositions for this use.
Type:
Grant
Filed:
August 7, 2006
Date of Patent:
February 24, 2009
Assignee:
VIA Pharmaceuticals, Inc.
Inventors:
Raymond Tabibiazar, Melisa Cooper, Thomas Quertermous, Adeoye Olukotun
Abstract: The invention relates to compounds having PDE2 inhibitory activities, as well as therapeutic methods by administering said compounds, in particular for treating various diseases of the central or peripheral nervous system. It further deals with pharmaceutical compositions comprising said compounds and methods for preparing said compounds.
Abstract: The invention concerns novel benzodiazepine derivatives and their uses in the field of therapeutics particularly for treating pathologies involving the activity of a cyclic nucleotide phosphodiesterase. It also concerns methods for preparing them and novel synthesis intermediates.
Type:
Grant
Filed:
June 7, 2002
Date of Patent:
July 31, 2007
Assignee:
Via Pharmaceuticals, Inc.
Inventors:
Jean-Jacques Bourguignon, Yan Lagouge, Claire Lugnier, Eveline Klotz, Jean-Paul Macher, Pierre Raboisson, Dominique Schultz