Abstract: A method and system for assisting the safe operation of a train adapted to be operated by a locomotive operating crew comprises generating GPS-located critical information at a central location, the GPS-located critical information being based at least in part on one or more railroad maps and one or more train dispatcher information systems; monitoring the real-time location of the train with a GPS device on-board the train; and generating alerts for the locomotive operating crew based on the GPS-located critical information and the real time location of the train, so that the crew is alerted as to upcoming changes to be implemented.