Abstract: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
Type:
Application
Filed:
April 25, 2011
Publication date:
December 15, 2011
Applicant:
VIAMET PHARMACEUTICALS, INC.
Inventors:
William J. Hoekstra, Robert J. Schotzinger, Stephen W. Rafferty
Abstract: The presently disclosed subject matter is described to metalloenzyme inhibitors having metal binding moieties linked to a targeting moiety through a linking group or a direct bond, method of screening for metalloenzyme inhibitors, and methods for treating a metalloenzyme related disorder by administering a metalloenzyme inhibitor to a subject in need of treatment thereof.
Type:
Application
Filed:
December 3, 2008
Publication date:
January 20, 2011
Applicant:
Viamet Pharmaceuticals, Inc.
Inventors:
Robert J. Schotzinger, William J. Hoekstra
Abstract: The presently disclosed subject matter is directed to metallo-oxidoreductase inhibitors having metal binding moities linked to a targeting moiety through a linking group or a direct bond, methods for screening for metallo-oxidoreductase inhibitors, and methods of treating an oxidoreductase related disorder by administering a metallo-oxidoreductase inhibitor to a subject in need of treatment thereof.
Type:
Application
Filed:
November 21, 2007
Publication date:
December 2, 2010
Applicant:
Viamet Pharmaceuticals, Inc.
Inventors:
Robert J. Schotzinger, William J. Hoekstra
Abstract: The present invention is directed to methods for screening for metallohydrolase inhibitors using metal binding moieties in combination with targeting moieties.
Abstract: The present invention is directed to compositions and methods of screening apoproteins for the elucidation of modulators of metalation of apoproteins.
Type:
Application
Filed:
October 20, 2006
Publication date:
December 25, 2008
Applicant:
Viamet Pharmaceuticals, Inc
Inventors:
Herbert Holden Thorp, JR., Thomas V. O'Halloran