Abstract: Provided herein are protein kinase inhibitors, which, in one aspect are selective inhibitors of HipK4. Pharmaceutical compositions and medical uses for the disclosed inhibitors are also provided.
Abstract: Method of treating cancer, such as a metastatic cancer, with inhibitors of homeodomain interacting protein kinase 4 (HIPK4) are provided. Related therapeutic compositions are also disclosed.
Type:
Application
Filed:
February 19, 2020
Publication date:
June 9, 2022
Applicants:
Board of Regents, The University of Texas System, Vibliome Therapeutics, LLC