Abstract: The present invention concerns methods and systems for analysis of drug resistance in HIV-1. More specifically, the invention provides methods for predicting drug resistance by correlating genotypic information with phenotypic profiles. The methods allow the identification of primary and secondary resistance-associated mutations for new and existing drugs and for calculating the contribution of mutations and combinations of mutations to resistance and hyper-susceptibility.
Type:
Application
Filed:
December 10, 2009
Publication date:
June 24, 2010
Applicant:
VICRO BVBA
Inventors:
Herwig Gaston Emiel Van Marck, Tim Gerrit Van Den Bulcke, Hans Victor Vermeiren