Abstract: The present invention relates to improved methods for tissue engineering including tissue transplantation, augmentation and regeneration, and more particularly, a method for the generation of donor vascularized tissue suitable for use in tissue transplantation, augmentation and/or repair. The present invention enables the use of a support matrix in the generation of an anatomical construct comprising the donor vascular tissue. The support matrix may be devised such that it has dimensions of a size and shape adapted to simulate those of tissue to be transplanted, augmented and/or repaired. The methods and support matrix of the present invention may also find application as a means for delivering a desirable gene product to a subject. The method and support matrix of the present invention is conveniently made available in the form of a kit, for use in the field of tissue engineering.

Abstract: Improved methods for tissue engineering including tissue transplantation, augmentation and regeneration are described. These methods utilize a support matrix in the generation of an anatomical construct that includes donor vascularized tissue. The support matrix may be devised such that it has size and shape adapted to simulate the dimensions of tissue to be transplanted, augmented and/or repaired.

Abstract: The present invention relates generally to improved methods for tissue engineering including tissue transplantation, augmentation and regeneration. More particularly, the present invention provides a method for the generation of donor vascularized tissue suitable for use in tissue transplantation, augmentation and/or repair. The present invention further enables the use of a support matrix in the generation of an anatomical construct comprising the donor vascular tissue. The support matrix may be devised such that it has dimensions of a size and shape adapted to simulate those of tissue to be transplanted, augmented and/or repaired. In addition to its use in tissue repair, the methods and support matrix of the present invention may also find application as a means for delivering a desirable gene product to a subject. The method and support matrix of the present invention is conveniently be made available in the form of a kit, for use generally in the field of tissue engineering.