Patents Assigned to Vipont Laboratories, Inc.
  • Production of purity benzo-c-phenanthridine alkaloid salts
    Patent number: 4769452
    Abstract: A method of extracting benzo-c-phenanthridine alkaloids from plants of the families Papaveraceae, Fumariaceae, and Berberidaceae, comprising grinding the plant, extracting the ground plant with acidulated methanol or acidulated ethanol, precipitating the extract with an acid salt soluble in the solvent used, redissolving the precipitated salt in water, adding sufficient acid to form a precipitate, and collecting the precipitate so formed.
    Type: Grant
    Filed: June 18, 1987
    Date of Patent: September 6, 1988
    Assignee: Vipont Laboratories, Inc.
    Inventor: Richard T. Boulware
  • Method for inhibiting the release of histamine
    Patent number: 4737503
    Abstract: The present invention deals with the inhibition of histamine release from mammalian mast cells by contacting such cells with sanguinarine, a benzophenanthridine alkaloid.
    Type: Grant
    Filed: October 8, 1986
    Date of Patent: April 12, 1988
    Assignee: Vipont Laboratories, Inc.
    Inventors: Seizaburo Sakamoto, Katsumi Sugiyama
  • Method for inhibiting bone resorption and collagenase release
    Patent number: 4735945
    Abstract: Method of inhibiting bone resorption and collagenase release in mammalian periodontal subjects using a benzo-c-phenanthridine alkaloid compound.
    Type: Grant
    Filed: March 13, 1986
    Date of Patent: April 5, 1988
    Assignee: Vipont Laboratories, Inc.
    Inventors: Seizaburo Sakamoto, Masako Sakamoto
  • Sanguinarine dental compositions with hydrated silica
    Patent number: 4689216
    Abstract: Dentifrices containing sanguinarine of superior stability and increased uptake into dental plaque are attained by the inclusion of hydrated silica as an abrasive.
    Type: Grant
    Filed: March 20, 1986
    Date of Patent: August 25, 1987
    Assignee: Vipont Laboratories, Inc.
    Inventor: James A. Greene
  • Method for treating periodontal disease
    Patent number: 4683133
    Abstract: A self-administerable method of treating periodontal disease by providing a dilute aqueous solution of a non-toxic benzo-c-phenanthridine salt, pumping the solution through an orifice to provide a pulsating jet stream that is capable of penetrating directly into the periodontal pockets associated with periodontal disease, and applying the jet stream to diseased gingival tissue and into the periodontal pockets.
    Type: Grant
    Filed: August 20, 1985
    Date of Patent: July 28, 1987
    Assignee: Vipont Laboratories, Inc.
    Inventor: G. Lee Southard
  • Antimicrobial agent
    Patent number: 4599228
    Abstract: An antimicrobial agent comprising a mineral acid salt of a benzophenanthridine alkaloid in a mixture with a metal salt of an acid.
    Type: Grant
    Filed: January 25, 1984
    Date of Patent: July 8, 1986
    Assignee: Vipont Laboratories, Inc.
    Inventor: Peter A. Ladanyi
  • Antimicrobial plaque disclosing agent
    Patent number: 4590061
    Abstract: Benzo-c-phenanthridine salts, either pure salts or salts precipitated form extracts of plants selected form the group consisting of Sanguinaria canadensis, Macleaya cordata, Corydalis sevctvozii, C. ledebouni, Chelidonium majus, and mixtures thereof, are effective agents for disclosing plaque in the oral cavity under long wavelength ultraviolet light.
    Type: Grant
    Filed: May 10, 1985
    Date of Patent: May 20, 1986
    Assignee: Vipont Laboratories, Inc.
    Inventor: George L. Southard
  • Plaque disclosing agent
    Patent number: 4517172
    Abstract: Salts of sanguinarine, either pure salts or a mixture of said salts precipitated from extracts of plants selected from the group consisting of Sanguinaria canadensis, Macleya cordata, Corydalis sevctvozii, C. ledebouni, Chelidonium majus, and mixtures thereon, are effective agents for disclosing plaque in the oral cavity under long wavelength ultraviolet light.
    Type: Grant
    Filed: December 29, 1983
    Date of Patent: May 14, 1985
    Assignee: Vipont Laboratories, Inc.
    Inventor: George L. Southard