Abstract: Methods and assays for disease prognosis, detection and treatment monitoring are provided. The assays and methods measure functional immune responses to disease modified biomolecules (DMBs) that are characteristic of a disease of interest. Exemplary diseases of interest include rheumatoid arthritis (RA), for which citruUinated peptides or proteins (CPs), are characteristic DMBs.
Type:
Application
Filed:
June 29, 2012
Publication date:
August 14, 2014
Applicant:
VIRACOR-IBT LABORATORIES
Inventors:
Jianrong Lou, Brad L. Stewart, Nathaniel Rill
Abstract: In certain embodiments, the present invention relates to methods, compositions, and kits for diagnosing autoimmune chronic urticaria. For example, in certain embodiments, such methods generally comprise detecting the presence of auto-antibodies to cell-surface IgE receptors or cell-bound IgE in a patient.
Type:
Grant
Filed:
October 7, 2010
Date of Patent:
August 7, 2012
Assignee:
Viracor-IBT Laboratories, Inc.
Inventors:
John Frederick Halsey, Michelle Lee Altrich
Abstract: In certain embodiments, the present invention relates to methods, compositions, and kits for diagnosing autoimmune chronic urticaria. For example, in certain embodiments, such methods generally comprise detecting the presence of auto-antibodies to cell-surface IgE receptors or cell-bound IgE in a patient.
Type:
Grant
Filed:
September 10, 2007
Date of Patent:
November 2, 2010
Assignee:
Viracor-IBT Laboratories, Inc.
Inventors:
John Frederick Halsey, Michelle Lee Altrich