Patents Assigned to Virbac
  • Patent number: 5747057
    Abstract: The invention comprises a composition of matter containing a matrix, a plasticizer and pyriproxifen for controlling fleas.
    Type: Grant
    Filed: April 1, 1996
    Date of Patent: May 5, 1998
    Assignee: Virbac, Inc.
    Inventor: Thomas A. Miller
  • Patent number: 5728719
    Abstract: The present invention is a method for controlling ectoparasites. More particularly, the invention relates to a method of treatment in which the warm blooded animal is dosed with an ovicidally effective amount of a heterocyclic nitrogen compound selected from the group represented by the formula: ##STR1## wherein R.sub.1, is either one of the following groups: ##STR2## in which R.sub.7, R.sub.8, R.sub.9, R.sub.10, R.sub.11, R.sub.12, R.sub.13, R.sub.14, R.sub.15, R.sub.16, and R.sub.17 are, the same or different, each a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 alkoxy group, a C.sub.1 -C.sub.4 alkylthio group, a trifluoro methyl group or a vitro group, R.sub.18, R.sub.19, R.sub.20 and R.sub.21 are, the same or different, each a hydrogen atom or a methyl group, k is an integer of 0 to 1 and 1 is an integer of 0 to 3; R.sub.2 and R.sub.3 are, the same or different, each a hydrogen atom, a halogen atom or a methyl group; R.sub.4 is a halogen atom or a methyl group; R.sub.5 and R.sub.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: March 17, 1998
    Assignee: Virbac, Inc.
    Inventor: Thomas A. Miller
  • Patent number: 5683722
    Abstract: A dosage form for orally administering chemical or medicinal substances such as vitamins, trace elements, amino acids, nutritive substances, vaccines, etc., to domestic or wild animals, and a method for preparing same, are disclosed. Said dosage form includes: a porous water-soluble central core containing binders selected from polypeptides, polysaccharides, polymers and colloids, and/or diluents selected from polyols, metal oxides, carbonates, phosphates and microcrystalline cellulose, and an effective amount of at least one bioactive substance; and a palatable hydrophobic outer layer containing at least one lipid substance selected from fatty alcohols, fatty acids, glycerol esters, hydrogenated oils, waxes, paraffin, lanolin, coconut oil and fatty acid salts; a polymeric agent for modulating the disintegration and adhesion of said outer layer, and natural or synthetic palatable substances.
    Type: Grant
    Filed: August 1, 1996
    Date of Patent: November 4, 1997
    Assignee: Virbac S.A.
    Inventors: Guy Derrieu, Andre Aubert, Bernard Raynier, Carolin L. Schumacher
  • Patent number: 5656440
    Abstract: Nucleotidic sequences coding for the bovine adrenergic-.beta..sub.3 receiver (RA.beta..sub.3), utilization of said sequences as probes and for the expression of peptides and/or fragments thereof having an activity of bovine RA.beta..sub.3, vectors useful for said expression, as well as cellular hosts containing said vector. Polyclonal and monoclonal antibodies raised against said peptides and usable, particularly for the detection of bovine adrenergic-.beta..sub.3 receivers, as well as method for screening substances, with agonist or antagonist action in relation to peptides having an adrenergic-.beta..sub.3 receiver activity and kits for the detection of the affinity degrees of different substances for said peptides having an adrenergic-.beta..sub.3 receiver activity. Transgenic and recombinant mice containing said nucleotidic sequence.
    Type: Grant
    Filed: February 21, 1995
    Date of Patent: August 12, 1997
    Assignees: Virbac, Vetigen
    Inventors: Gerlinda Lenzen, Archana Kapoor
  • Patent number: 5632999
    Abstract: The invention comprises a method of controlling fleas which includes continuously administering to the haircoat of a homeothermic animal an ovicidally effective amount of 2-(1-methyl-2-(4-phenoxyphenoxy)ethoxy)pyridine (pyriproxifen) from a sustained release matrix at a rate of 0.1 mcg/kg/day to 100 mcg/kg/day. The method may also include the use of additional ingredients such as insecticides, plasticizers, lubricants and antioxidants in a sustained release matrix.
    Type: Grant
    Filed: August 18, 1993
    Date of Patent: May 27, 1997
    Assignee: Virbac, Inc.
    Inventor: Thomas A. Miller
  • Patent number: 5595762
    Abstract: Stabilized pulverulent active agents, compositions containing them and also process for obtaining them; such stabilized active agents enable dry and stable pharmaceutical, dietary, nutritional or cosmetic compositions to be obtained, in which the properties of the said active agents are neither modified nor impaired. Such stabilized active agents are stabilized by coating with a coating composition comprising:-- at least one film-forming agent, in proportions of between 2 and 25% by weight of the final mass, selected from polyvinylpyrrolidones (povidone), polyvinyl alcohols, vinylpyrrolidone/vinyl acetate copolymer, vinylpyrrolidone/polyvinyl alcohol copolymer, cellulose derivatives such as cellulose acetate, cellulose acetate phthalate, cellulose butyrate, ethylcellulose and methylcellulose, acrylic and methacrylic polymers and copolymers and vegetable, animal or synthetic waxes, and-- at least one pore-forming agent, in proportions of between 0 and 5%, by weight preferably of between 0.
    Type: Grant
    Filed: November 30, 1993
    Date of Patent: January 21, 1997
    Assignee: Laboratoires Virbac
    Inventors: Guy Derrieu, Bernard Raynier
  • Patent number: 5527523
    Abstract: Hydroquinone amino-acid esters having formula (I), pharmaceutical or cosmetic compositions containing them, particularly dermatological compositions having pigment-removing activity, and the pharmaceutical, cosmetic or aesthetic uses thereof. The preparation of these novel hydroquinone esters from natural amino-acid derivatives is also described.
    Type: Grant
    Filed: October 13, 1992
    Date of Patent: June 18, 1996
    Assignee: Virbac S.A.
    Inventors: Claude Laruelle, Bernard Raynier, Guy Derrieu
  • Patent number: 5439924
    Abstract: The present invention is a method for controlling ectoparasites. More particularly, the invention relates to a method of treatment in which the warm blooded animal is dosed with an ovicidally effective amount of a heterocyclic nitrogen compound selected from the group represented by the formula: ##STR1## wherein R.sub.1, is either one of the following groups: ##STR2## R.sub.2 and R.sub.3 are the same or different, each a hydrogen atom, a halogen atom or a methyl group; R.sub.4 is a halogen atom or a methyl group; R.sub.5 and R.sub.6 are the same or different, each a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 haloalkyl group or a C.sub.1 -C.sub.4 haloalkoxy group; X, Y and Z are the same or different, each an oxygen atom, a sulfur atom or a methylene group, which is transmitted to the ectoparasite by the animal's blood. In a further embodiment, a compound selected from the group consisting of ivermectin, milbemycin, milbemycin oxime, moxidectin and avermectin and avermectin derivatives.
    Type: Grant
    Filed: March 17, 1994
    Date of Patent: August 8, 1995
    Assignee: Virbac, Inc.
    Inventor: Thomas A. Miller
  • Patent number: 5338533
    Abstract: A device enabling one or more active principles or substances to be released in a gradual and programmed manner, wherein the device can be obtained by:a) preparing a powder comprising a resin or polymer matrix in which at least one suitable plasticizer is fully absorbed by heating the plasticizer and hot spraying it onto the matrix while it is being maintained in temperature, thereby saturating the resin with plasticizer;b) cooling the powder obtained in a) to a temperature below 30.degree. C;c) cold mixing the powder obtained in b) with at least 5% of at least one carrier of active principle; thend) adding the active principle(s); ande) suitably forming the powder obtained in d) by any appropriate means, which device releases the active principle uniformly and completely.The device further includes a covering made of a polymer which is impermeable to the active principle(s) and which covers a portion of the surface of the device.
    Type: Grant
    Filed: May 27, 1992
    Date of Patent: August 16, 1994
    Assignee: Laboratoires Virbac
    Inventor: Guy Derrieu
  • Patent number: 4823800
    Abstract: An ultrasonic probe is adapted to be implanted in a human or animal body in contact with a wall of an organ to allow exploration of the organ by ultrasonics, inter alia by the Doppler effect. It comprises a support for a piezo-electric transmitter/receiver transducer, and a cover which covers the transducer and at least that part of the support which is remote from the organ. The transmitting/receiving surface of the transducer is in contact with a surface of the support, which is interposed between the transducer means and the organ. The probe also has conductors attached to the transducer extending to the outside of the body to carry the information transmitted/received by the probe. The support and the cover have a configuration and shape such as to allow the probe to be removed from the body without a complex surgical operation, particularly by simply pulling from outside on the connecting means.
    Type: Grant
    Filed: August 11, 1986
    Date of Patent: April 25, 1989
    Assignee: Virbac, a French Corporation
    Inventor: Andre C. Compos
  • Patent number: 4643893
    Abstract: There is disclosed a novel device intended to permit the regular and continuous release of chemical substances, including medicaments, and this, over a very long period of time, the release of the active substances following a predetermined kinetic effect from an insoluble polymeric matrix to a liquid medium which can be, particularly, that of an animal or human organism. The device has a specific density to remain in an animal rumen. There is also disclosed a method for treating animals by means of such devices.
    Type: Grant
    Filed: March 6, 1985
    Date of Patent: February 17, 1987
    Assignee: C.R.B. Virbac S.A.
    Inventors: Frederic M. Ascher, Jacques A. Cuvelier