Patents Assigned to Virgina Commonwealth University
  • Polyvalent chimeric OSPC vaccinogen and diagnostic antigen
    Patent number: 9556239
    Abstract: A chimeric polyvalent recombinant protein for use as a vaccine and diagnostic for Lyme disease is provided. The chimeric protein comprises epitopes of the loop 5 region and/or the alpha helix 5 region of outer surface protein C (OspC) types. The OspC types may be associated with mammaliran Borrelia infections.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: January 31, 2017
    Assignee: Virgina Commonwealth University
    Inventors: Richard T. Marconi, Christopher Earnhart
  • Compounds having antiestrogenic and tissue selective estrogenic properties, and compounds with anti-androgenic properties for treatment of prostate cancer and androgen receptor dependent diseases
    Patent number: 7601739
    Abstract: Compounds for the treatment of estrogen-receptor related maladies are provided. Compounds with anti-androgenic properties also are provided. In particular, the invention provides compounds that are tetrahydroquinoline phenylamide derivatives and are useful for the treatment of breast and prostate cancer, and osteoporosis.
    Type: Grant
    Filed: February 8, 2006
    Date of Patent: October 13, 2009
    Assignee: Virgina Commonwealth University
    Inventors: Richmond Danso-Danquah, Donald J. Abraham, Hsiang-Ru Lin, Jim Christian Burnett