Patents Assigned to Virginia State University
  • Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide
    Patent number: 12226423
    Abstract: Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions.
    Type: Grant
    Filed: June 28, 2022
    Date of Patent: February 18, 2025
    Assignees: Virginia Commonwealth University, Durect Corporation, The United States Government as Represented by The Department of Veterans Affairs
    Inventors: Shunlin Ren, Leyuan Xu, Yanxia Ning, Jin Koung Kim, WeiQi Lin, Andrew R. Miksztal, Hongwei Wu, Min L. Lee
  • Feed compositions comprising purslane leaves and methods of using thereof
    Patent number: 5688508
    Abstract: The present invention is drawn to feed compositions including purslane leaves harvested at bloom. The present invention is further drawn to methods of reducing serum cholesterol and triglycerides with the present feed compositions of purslane leaves, as well as methods of preventing and treating coronary heart disease with the feed compositions.
    Type: Grant
    Filed: February 21, 1995
    Date of Patent: November 18, 1997
    Assignee: Virginia State University
    Inventors: Michael O. Ezekwe, Thomas R. Omara-Alwala, Tadesse Mebrahtu