Abstract: An example device for repairing a tissue is described herein. The device can include a flexible carrier layer, and a support member including a plurality of micro-protrusions extending therefrom. The support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the tissue, and the micro-protrusions can be configured to mechanically interface with the tissue.

Abstract: The present invention relates generally to a therapeutic pulse generator system used to provide energy efficient stimulation/pacing by causing controlled cellular depolarization based on pre-measured charge transfer. This is accomplished by periodic electrical characterization of the electrode-tissue interface. Each channel of stimulation is programmed individually enabling the clinician to customize the therapeutic protocol. Energy efficiency may also be further improved through the use of a multi-channel lead in which the amount of energy required for each subsequent channel may be set to be less than the previous channel. The total energy required for multi-channel stimulation/pacing has also been shown to be less than that required by a single channel for the same therapeutic benefit.

Abstract: A system for monitoring the material changes in a structure is disclosed through the use monitoring instruments embedded within the structure. The instruments have at least one sensor with electrodes in contact with the surrounding material and electronics that are contained within the instrument. The sensor signals are converted to digital and transmitted to an external data logger or computer for display of the digitized signals. The connection between the microcontroller and the data logger can be either through hardwire or RF. Power is provided to the electronic sensors through either external or local methods. A power management system can be used to place the electronics into a sleep mode when not in use. The electronics are encapsulated within potting material within an instrument case that is manufactured from a material having a flexural modulus equal to, or greater than, the surrounding material to prevent mechanical failure of the device before failure of the surrounding material.