Patents Assigned to Virginia
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Publication number: 20020059421Abstract: Methods and systems for providing a network communication status description based on user characteristics. The techniques receive a status indication from a first networked computer in response to a user's request for information and determine one or more characteristics of the user who issued the request. The techniques provide a status description based on the status indication and the determined characteristics of the user (e.g., a preferred language).Type: ApplicationFiled: January 15, 2002Publication date: May 16, 2002Applicant: America Online, a Dulles, Virginia corporationInventor: C. Hudson Hendren
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Publication number: 20020052041Abstract: The present invention relates to methods for the production of high titers of serum-free lytic viruses in a hollow fiber cartridge capillary system. The invention further relates to methods of infecting target cells at high multiplicity and for producing high concentrations of transduced target cells.Type: ApplicationFiled: September 6, 2001Publication date: May 2, 2002Applicant: University of Virginia Patent Foundation.Inventors: Leland W.K. Chung, Thomas A. Gardner, Chinghai Kao, Song-Chu Ko
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Patent number: 6371917Abstract: In a method of identifying gaseous bubbles in a liquid, an ultrasound contrast agent is introduced into the liquid so as to form gaseous bubbles in the liquid. A first ultrasound pulse centered at a first frequency is directed onto the bubbles so as to cause the bubbles to undergo a first oscillating size change and produce a first oscillating echo signal corresponding thereto. The first oscillating echo signal produced by the bubbles is detected, and the bubbles are identified based upon the detected first echo signal.Type: GrantFiled: August 31, 2000Date of Patent: April 16, 2002Assignee: University of Virginia Patent FoundationInventors: Katherine W. Ferrara, Karen Elizabeth Morgan, Paul Dayton
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Patent number: 6367467Abstract: A holding unit is provided to support an ingot in a semiconductor wafer sawing machine, which minimizes the instability of a blade during a sawing process. The holding unit is formed from substantially the same material as an ingot resting thereon. The holding unit includes a top surface for receiving an ingot, a bottom surface, a pair of side walls, and a cavity formed in the holding unit. The cavity forms a plurality of break points in the holding unit. When contacted by the blade, the holding unit fractures at the break points to minimize the chipping of the wafer.Type: GrantFiled: June 18, 1999Date of Patent: April 9, 2002Assignee: Virginia SemiconductorInventors: A. Dempsey McGregor, Marshall P. Toombs, James E. Brooks, Benjamin J. Meadows
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Patent number: 6354327Abstract: According to principles of this invention, an override controller is structured for being placed in pressurized fluid lines between a valve position transducer and a valve position actuator of an automatic position-controlled valve assembly, with the override controller receiving uncontrolled supply pressurized fluid and having an exhaust. The override controller receives pressurized fluid at first and second inlet ports from the valve position transducer and furnishes this pressurized fluid to the valve position actuator through first and second outlet ports for controlling the position of the valve during normal operation. However, valve mechanisms of the override controller can also be placed in positions for stopping flow of pressurized fluid through the first and second inlet ports and providing fluid flow from the uncontrolled pressurized fluid to the first and second outlet ports for controlling the position of an industrial valve during override operation.Type: GrantFiled: July 31, 2000Date of Patent: March 12, 2002Assignee: Virginia Valve CompanyInventor: John Mayhew
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Patent number: 6355142Abstract: Controlling the velocity of a jet of foamed furnish leaving the slice of a pressurized headbox of a paper or a tissue making machine by measuring the density and pressure of a flow of foamed furnish provided by a pump to estimate an atmospheric pressure air content, measuring the pressure of the foamed furnish in the headbox, using the estimated atmospheric pressure air content and the measured pressure in the headbox to estimate the current velocity of said jet of foamed furnish, comparing the estimated current velocity with a target velocity and controlling the pump to move the estimated and target velocities closer to each other. An alternate embodiment controls jet velocity on the basis of comparing estimated and target headbox pressures.Type: GrantFiled: November 16, 1992Date of Patent: March 12, 2002Assignee: Fort James Corporation of VirginiaInventor: Frederick W. Ahrens
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Patent number: 6355480Abstract: The present invention relates to compositions and methods for screening compounds that modulate meiotic progression. In particular, it relates to compositions comprising nucleotides from the mouse 5′ regulatory region, and transcriptionally active fragments thereof, that control the expression of a testis-enriched protein, SP-10. Specifically provided are expression vectors, host cells, and transgenic animals. The SP-10 promoter controls the expression of a heterologous gene, e.g., green fluorescent protein. The invention relates to methods for using the vectors, cells, and animals for screening candidate molecules for agonists and antagonists of sperm development and fertilization. Methods for using molecules and compounds identified by the screening assays for therapeutic treatments are provided.Type: GrantFiled: June 25, 1999Date of Patent: March 12, 2002Assignee: University of Virginia Patent FoundationInventors: Prabhakara P. Reddi, Charles J. Flickinger, John C. Herr
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Patent number: 6350740Abstract: The invention provides a method for enhancing the water solubility of cytotoxic trans-platinum complexes. The present invention also provides a method for killing tumor cells, and a method for the treatment of tumors by the administration of a cytotoxic platinum coordination complex of the general formula SP4-2-[PtX(L)(L′)(B)]+.Type: GrantFiled: September 5, 2000Date of Patent: February 26, 2002Assignee: Virginia Commonwealth UniversityInventor: Nicholas Farrell
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Patent number: 6349044Abstract: A three-level DC-to-DC converter is provided having zero-voltage and zero-current switching (ZVZCS). A flying capacitor is provided on the primary side of the converter to achieve zero voltage switching (ZVS). In addition, during freewheeling (i.e., when no power is being transferred from the primary side to the secondary side), an auxiliary power source is provided to eliminate the circulating energy and to achieve zero current switching (ZCS) for the commutation switches.Type: GrantFiled: September 8, 2000Date of Patent: February 19, 2002Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: Francisco Canales-Abarca, Peter M. Barbosa, Fred C. Lee
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Patent number: 6346226Abstract: A method of making anisotropic carbon foam material includes de-ashing and hydrogenating bituminous coal, separating asphaltenes from oils contained in the coke precursor, coking the material to create a carbon foam. In one embodiment of the invention, the carbon foam is subsequently graphitized. The pores within the foam material are preferably generally of equal size. The pore size and carbon foam material density may be controlled by (a) altering the percentage volatiles contained within the asphaltenes to be coked, (b) mixing the asphaltenes with different coking precursors which are isotropic in nature, or (c) modifying the pressure under which coking is effected. In another embodiment of the invention, solvent separation is employed on raw bituminous coal and an isotropic carbon foam is provided. A related carbon foam product is disclosed. The carbon foam materials of the present invention are characterized by having high compressive strength as compared with prior known carbon foam materials.Type: GrantFiled: September 25, 2000Date of Patent: February 12, 2002Assignee: West Virginia UniversityInventors: Alfred H. Stiller, Peter G. Stansberry, John W. Zondlo
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Patent number: 6344596Abstract: Recombinant Factor IX characterized by a high percentage of active protein can be obtained in the milk of transgenic animals that incorporate chimeric DNA molecules according to the present invention. Transgenic animals of the present invention are produced by introducing into developing embryos DNA that encodes Factor IX, such that the foreign DNA is stably incorporated in the DNA of germ line cells of the mature animal. Particularly efficient expression was accomplished using a chimeric construct comprising a mammary gland specific promoter, Factor IX cDNA that lacked the complete or any portion of the 5′-untranslated and 3′-untranslated region, which is substituted with a 5′- and 3′-end of the mouse whey acidic protein gene. In vitro cell cultures of cells explanted from the transgenic mammal of the invention and methods of producing Factor IX from such said culture and methods of treating hemophilia B are also described.Type: GrantFiled: September 15, 1999Date of Patent: February 5, 2002Assignees: American Red Cross, Virginia Tech Intellectual Properties, Inc.Inventors: William H. Velander, William N. Drohan, Henryk Lubon, John L. Johnson
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Patent number: 6342242Abstract: Seaweed harvested from the ocean when ground as an intact meal or exposed to alkaline hydrolsis extraction procedure resulting in a water soluble form provides a feed ingredient with mineral composition and plant growth regulating activity when included as a pasture treatment or feed ingredient for mammals and poultry, resulting in enhanced immune function, enhanced health, weight gain, and meat grade quality. Steers grazing seaweed extract treated forage continued to exhibit enhanced immune function after entering feedlot phase finishin with no seaweed extract diet supplement.Type: GrantFiled: February 27, 1998Date of Patent: January 29, 2002Assignees: Texas Tech University, Virginia Tech Intellectual Properties, Inc.Inventors: Vivien Gore Allen, Kevin R. Pond, Korinn E. Saker, Joseph P. Fontenot
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Patent number: 6341212Abstract: A system which contains a plurality of examinee systems connected over the Internet to an exam distribution server. The exam distribution server connects to an exam database system which contains a plurality of exam questions that have been approved by one or more exam question approvers. The exam database system may store a plurality of potential exam questions for each of a plurality of sections of the examination, including a section for web search and evaluation, a section for general computing concepts, a web page design section, a section for using presentation software, a section relating to spreadsheets and word processing, and a section relating to legal and ethical issues. An exam administrator system then generates an exam through an exam generation module that selects a predetermined number of questions in each of the predetermined sections of the examination and presents the proposed exam to the exam administration system.Type: GrantFiled: December 17, 1999Date of Patent: January 22, 2002Assignee: Virginia Foundation for Independent CollegesInventors: Anil M. Shende, Linda N. Dalch, Mark R. Warner
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Publication number: 20020004110Abstract: A heat insulating paper cup having an improved seal. The cup can include a body member having an inside surface and an outside surface, and a bottom panel member having a upper surface and a bottom surface. The body member is coated (or in some instances partially coated) on its outside surface with a foamed low density polyethylene, and on its inside surface with an unfoamed modified low density polyethylene. The bottom panel member is coated on its upper surface with a foamed or an unfoamed low density polyethylene or foamed or unfoamed modified low density polyethylene. The body member and bottom panel member are oriented and joined to form a heat seal at an interface between a portion of the unfoamed modified low density polyethylene coated on the inside surface of the body member and a portion of unfoamed low density polyethylene or unfoamed modified low density polyethylene coated on the upper surface of the bottom panel member.Type: ApplicationFiled: June 6, 1997Publication date: January 10, 2002Applicant: James River Corporation of VirginiaInventors: MICHAEL A. BREINING, WILLIAM R. PUCCI, DAVID C. BROWN, RICHARD A. SEGAN, DONALD C. MCCARTHY, WALTER MALAKHOW
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Patent number: 6337801Abstract: Zero current transition (ZCT) topologies are presented for three-phase inverters and rectifiers. Such devices are used for example in AC adjustable speed drives for so-called zero-emission vehicles (i.e., electric and hybrid combustion/electric automobiles). Compared to existing three-phase ZCT techniques, the number of auxiliary switches is reduced from six to three, while not altering the necessary device rating. Correspondingly, the number of gate-drivers for the auxiliary switches is also reduced to three. Meanwhile, the merits of the existing three-phase ZCT techniques are still retained, i.e., all the main switches and the auxiliary switches are turned on and turned off under zero-current conditions, and the independent commutation for each main switch is achieved. The desired soft-switching features are achieved. Therefore, this invention will contribute to more cost-effective, reliable, and efficient high-performance three-phase inverters and rectifiers.Type: GrantFiled: December 15, 2000Date of Patent: January 8, 2002Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: Yong Li, Fred C. Lee
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Patent number: 6334121Abstract: A usage based pattern authenticator for monitoring and reporting on user usage patterns in an operating system using a set of security rules and user usage patterns. This computer system security tool authenticates users at the operating system level in multi-user operating systems. It supports system administrators in limiting the ability of unauthorized users to disrupt system operations using a neural network and set of rules to track usage patterns and flag suspicious activity on the system. The data collection mode collects and stores usage patterns of authenticated users. The training mode trains an artificial neural network and sets the interconnection weights of the network. The production mode monitors and reports on usage patterns, and optionally performs automatic responses when confronted with non-authenticated users.Type: GrantFiled: March 12, 1999Date of Patent: December 25, 2001Assignee: Virginia Commonwealth UniversityInventors: David Primeaux, Doraiswamy Sundar, Willard L. Robinson, Jr.
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Patent number: 6330469Abstract: In one aspect of the invention, there is provided a method and apparatus for early detection of subacute, potentially catastrophic infectious illness in a premature newborn infant. The method comprises: (a) continuously monitoring heart rate variability in the premature newborn infant; and (b) identifying at least one characteristic abnormality in the heart rate variability that is associated with the illness. This method can be use to diagnose illnesses such as, but not limited to, sepsis, necrotizing enterocolitis, pneumonia and meningitis. In another aspect, there is provided a method and apparatus for early detection of subacute, potentially catastrophic infectious illness in a patient.Type: GrantFiled: September 25, 2000Date of Patent: December 11, 2001Assignee: The University of Virginia Patent FoundationInventors: M. Pamela Griffin, J. Randall Moorman
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Patent number: 6330170Abstract: A soft-switched single-phase quasi-single-stage (QSS) bi-directional inverter/charger converts AC-DC or DC-AC. The inverter/charger comprises a push-pull inverter/rectifier on the dc-side, an isolation transformer which provides ohmic isolation and voltage scaling, two full-bridges on the ac side in cascade, a voltage clamp branch comprising a capacitive energy storage element in series with an active switch with its anti-parallel diode, a passive filter at the ac side to smooth out the high frequency switching voltage ripple at the output, and a corresponding PWM scheme to seamlessly control the converter to operate in all four quadrant operation modes in the output voltage and output current plane, and is capable of converting power in both directions.Type: GrantFiled: August 25, 2000Date of Patent: December 11, 2001Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: Kunrong Wang, Fred C. Lee
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Patent number: 6329500Abstract: The present invention relates to a composition and method for inhibiting TGF-&bgr; activity. The composition comprises a TGF-&bgr; neutralizing peptide derived from &agr;2-macroglobulin that binds to TGF-&bgr; and inhibits TGF-&bgr; activity.Type: GrantFiled: May 13, 1999Date of Patent: December 11, 2001Assignee: University of Virginia Patent FoundationInventors: Donna J. Webb, Steven L. Gonias
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Patent number: PP12350Abstract: The present invention is a new and distinct spring bearing red raspberry cultivar named ‘Emily’, which is capable of producing highly cohesive and firm fruit in the spring midseason, the fruit being larger and more durable than that of the standard cultivars. The cultivar is characterized by moderate suckering ability, small red thorns and its large and elongate fruit which have a much narrower cavity than standard cultivars. Because of this trait, the fruit of ‘Emily’ is structurally more sound than other cultivars.Type: GrantFiled: October 22, 1998Date of Patent: January 15, 2002Assignees: University of Maryland, Virginia Tech Intellectual Properties, Inc., University of Wisconsin at River FallsInventors: Harry Jan Swartz, Joseph A. Fiola, Herbert D. Stiles, Brian R. Smith