Abstract: A flow cytometer may include a vibration isolation structure on which a flow cytometer optical system assembly is supported when the flow cytometer is in an operational configuration. A shear protection structure may be positioned to protect a vibration isolation structure from damage during handling and shipping. A flow cytometer optical system assembly may include optical component units fixed in position on a support platform with adjustability of one or more optical features in the optical component units. A light-tight dichroic mirror unit may include a rotatably mounted dichroic mirror with a locking mechanism to permit re-setting angular positioning of a dichroic mirror.
Type:
Application
Filed:
June 2, 2015
Publication date:
July 13, 2017
Applicant:
VIROCYT, INC.
Inventors:
Kathy L. ROWLEN, Erica Dawson TENENT, Garrett S. WILSON, Christopher H. CONVERSE
Abstract: In a method for processing biological materials for flow cytometry evaluation for virus particles, a mixture including biological material and purification particles is centrifuged to prepare a centrifuged composition including a supernatant that may be further processed prior to the flow cytometry evaluation. The purification particles include porous cores functionalized to capture smaller-size impurities in a biological material sample and a porous size-exclusion shell surrounding the core to exclude larger-size components of the biological material from entering into the core. Multiple samples may be processed in multi-sample processing units. A product may contain a sealed container with the unit quantity of purification particle in a storage liquid and a kit may include such a sealed container and a centrifugal filter.
Type:
Grant
Filed:
November 20, 2015
Date of Patent:
January 17, 2017
Assignee:
VIROCYT, INC.
Inventors:
Kathy L. Rowlen, Erica Dawson Tenent, Lauren R. Wolfe