Abstract: A compound of formula (I) is useful as an antiviral agent, in particular for the treatment of influenza. A method for preparing the compound of formula (I) and a composition including the compound of formula (I) are described.
Type:
Application
Filed:
May 17, 2013
Publication date:
May 14, 2015
Applicant:
VIRONOVA AB
Inventors:
Mohammed Homman, Ngarita Kingi, Jan Bergman, Robert Berg
Abstract: A pharmaceutical composition for topical administration including 2,3-dimethyl-6-(N,N-dimethylaminoethyl)-6H-indolo-(2,3-b)quinoxaline (B-220) or a pharmaceutically acceptable salt thereof in a pharmaceutically acceptable carrier. The composition is useful for the treatment of herpes virus infections of the skin or mucous membranes in a mammal subject.
Abstract: A process for transforming a group >C?O (I) in a compound into a group >C?S (II) or into a tautomeric form of group (II) in a reaction giving a thionated reaction product, by use of crystalline P2S5.2 C5H5N as a thionating agent. A thionating agent which is crystalline P2S5.2 C5H5N.
Type:
Application
Filed:
February 3, 2012
Publication date:
April 25, 2013
Applicant:
VIRONOVA AB
Inventors:
Birgitta Pettersson, Vedran Hasimbegovic, Per H Svensson, Jan Bergman
Abstract: A compound of formula (I) wherein R1 is selected from H, F, Cl, Br, CF3, C1-C6 alkoxy and OH; R2 is selected from H and C1-C6 alkyl; n is 1-12; m is O or 1; Y is selected from CH2, NR3, (NR3R4)+X, O and S; R3 and R4 are independently selected from H and C1-C4 alkyl; and X? is selected from phannaceutically acceptable anions. A method of preparing the compound, its use as a pharmaceutical, and a method of treatment.
Type:
Grant
Filed:
January 22, 2007
Date of Patent:
December 13, 2011
Assignee:
Vironova AB
Inventors:
Mohammed Homman, Robert Engovist, Cecilia E Söderberg-Nauclér, Jan Bergman
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