Abstract: Thiol derivatives of general formula (II) have antiviral activity, particularly against influenza virus. In particular, the compound (4-(2-chloro-4-nitrophenyl)piperazin-1-yl)(4-(2-fluoro-6-methoxyphenyl)-1-methyl-1H-1,2,3-triazol-5-yl)methanone is provided. Methods of preparing the compounds are also described.
Type:
Grant
Filed:
June 6, 2016
Date of Patent:
June 13, 2017
Assignee:
VIRONOVA INFLUENZA AB
Inventors:
Mohammed Homman, Ngarita Kingi, Jan Bergman, Robert Berg
Abstract: A compound of formula (I) is useful as an antiviral agent, in particular for the treatment of influenza. A method for preparing the compound of formula (I) and a composition including the compound of formula (I) are described.
Type:
Grant
Filed:
May 17, 2013
Date of Patent:
June 7, 2016
Assignee:
VIRONOVA INFLUENZA AB
Inventors:
Mohammed Homman, Ngarita Kingi, Jan Bergman, Robert Berg