Abstract: An enterprise system and method for maintaining and transitioning humans to a human-like self-reliant entity is presented. Said system including at least one a biological, biomechatronic, and mechatronic entity with a biological or artificial neural network to at least one transform or maintain. Embodiments are provided to assist in the transition of human between a biological state to a bio-mechatronic and mechatronic entity. Said entity's biological, biomechatronic, and mechatronic subsystems are configured to communicate and interact with one another in order for said enterprise system to manage, configure, maintain, and sustain said entity throughout the entity's life-cycle. Subsystem embodiments and components supported by the enterprise system are presented.