Patents Assigned to Visigen Biotechnologies, Inc.
  • Methods for real-time single molecule sequence determination
    Patent number: 7329492
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Grant
    Filed: December 8, 2004
    Date of Patent: February 12, 2008
    Assignee: Visigen Biotechnologies, Inc.
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
    Patent number: 7211414
    Abstract: Nucleotide triphosphate probes containing a molecular and/or atomic tag on a a ? and/or ? phosphate group and/or a base moiety having a detectable property are disclosed, and kits and method for using the tagged nucleotides in sequencing reactions and various assay. Also, phosphate and polyphosphate molecular fidelity altering agents are disclosed.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: May 1, 2007
    Assignee: Visigen Biotechnologies, Inc.
    Inventors: Susan H. Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu