Abstract: The present invention relates generally to an automated reference indicator system. In one embodiment, the present invention provides a first reference indicator patch disposed near an area of interest, such as a wound, on an object, such as a human. A first image depicting the area of interest and the first reference indicator patch is captured and then input into a computer apparatus. A first set of data regarding the area of interest is then calculated by the computer apparatus based on an analysis of the first reference indicator patch and the area of interest. A second image of the area of interest and a second reference indicator patch disposed on at least a portion of the object is captured and subsequently input into the computer apparatus. The second image is typically taken at a time different from when the first image was taken. For example, the second image could be captured two weeks after the first image was captured.