Abstract: An imaging system includes a visible light source configured to output visible light and a near infrared laser light source configured to output an excitation laser light. The system also includes a camera assembly having: a housing with an opening configured to receive a combined light, which includes visible light and infrared fluorescence light. The combined light entering the housing along a combined light path, the combined light may include visible light and infrared fluorescence light; an aperture mechanism having an adjustable opening disposed along the combined light path; a beamsplitter configured to split the combined light into the visible light along a visible light path and the infrared fluorescence light along an infrared light path; a visible light sensor configured to receive the visible light and to generate visible light image data; and an infrared sensor configured to receive the infrared fluorescence light and to generate infrared fluorescence image data.

Abstract: A device and method for fluorescent imaging may include an imaging unit including a fluorescent camera with an optical detector that is configured to acquire a fluorescent image of a fluorescing sample, the image including raw pixel values. A user interface may display an image formed from display image pixels derived from the raw image pixels. A distance sensor may measure a distance to the fluorescing sample. A distance between the optical detector and fluorescing sample may be determined from the measured distance. A processing unit may obtain a gain value, match the determined distance to a distance value associated a respective gain range, and impose limits of the gain values range onto the gain value, to determine a limited gain value. The limited gain value may be applied to the raw image pixels, thereby deriving display image pixels.

Abstract: A novel dual-path-endoscope where a multi-function light source produces a first-light and a second-light toward an object. The first-light exhibits first-light-characteristics. The second-light exhibits second-light-characteristics different from the first-light-characteristics. The endoscope includes two light-paths, the disparity there between is larger than zero. Each light-path includes a respective pupil and a respective light-separator coupled with the pupil, transmitting there through one of the first-light and the second-light, associating the first-light and the second-light with a respective light-path. The dual-channel-imager includes two imager sensors, each associated with a respective light-path and optically coupled with a respective light-separator. Each imaging-sensor exhibits sensitivity to the characteristics of the respective one of the first-light and the second-light.

Abstract: A novel dual-path-endoscope where a multi-function light source produces a first-light and a second-light toward an object. The first-light exhibits first-light-characteristics. The second-light exhibits second-light-characteristics different from the first-light-characteristics. The endoscope includes two light-paths, the disparity there between is larger than zero. Each light-path includes a respective pupil and a respective light-separator coupled with the pupil, transmitting there through one of the first-light and the second-light, associating the first-light and the second-light with a respective light-path. The dual-channel-imager includes two imager sensors, each associated with a respective light-path and optically coupled with a respective light-separator. Each imaging-sensor exhibits sensitivity to the characteristics of the respective one of the first-light and the second-light.

Abstract: A novel dual-path-endoscope where a multi-function light source produces a first-light and a second-light toward an object. The first-light exhibits first-light-characteristics. The second-light exhibits second-light-characteristics different from the first-light-characteristics. The endoscope includes two light-paths, the disparity there between is larger than zero. Each light-path includes a respective pupil and a respective light-separator coupled with the pupil, transmitting there through one of the first-light and the second-light, associating the first-light and the second-light with a respective light-path. The dual-channel-imager includes two imaging sensors, each associated with a respective light-path and optically coupled with a respective light-separator. Each imaging-sensor exhibits sensitivity to the characteristics of the respective one of the first-light and the second-light.

Abstract: A device and method for fluorescent imaging may include an imaging unit including a fluorescent camera with an optical detector that is configured to acquire a fluorescent image of a fluorescing sample, the image including raw pixel values. A user interface may display an image formed from display image pixels derived from the raw image pixels. A distance sensor may measure a distance to the fluorescing sample. A distance between the optical detector and fluorescing sample may be determined from the measured distance. A processing unit may obtain a gain value, match the determined distance to a distance value associated a respective gain range, and impose limits of the gain values range onto the gain value, to determine a limited gain value. The limited gain value may be applied to the raw image pixels, thereby deriving display image pixels.

Abstract: A fluorescence imaging system including a light source, an optical system, camera and an excitation light filter, the optical system produces a non-uniform fluence excitation illumination beam for illuminating an object and promoting fluorescence emissions, the optical system is positioned between the light source and the object, the optical system modifies the non-uniform fluence illumination beam into a uniform fluence illumination beam and changes the divergence of the uniform fluence illumination beam, the camera has an array of pixels, the camera detects the fluorescence emissions and performs pixel intensity measurements for each of the pixels, the excitation light filter is positioned between the object and the camera and filters out the excitation illumination beam, such that the excitation illumination beam does not reach the camera.

Abstract: Fluorescence imaging illumination fiber including a first fiber, a second fiber, and a diffuser, the second fiber concentrically enfolding the first fiber, the diffuser is coupled at the end of the first fiber and the second fiber, the first fiber having a first angular output, the second fiber having a second angular output, the diffuser increasing the first angular output by a first value and increasing the second angular output by a second value, the first value exceeding the second value.

Abstract: A stereoscopic endoscope pupil configuration for embedding in a stereoscopic endoscope, the shape of the cross section of the stereoscopic endoscope is a predetermined closed two-dimensional shape, the stereoscopic endoscope pupil configuration including at least two pupils, each of the at least two pupils having a shape covering a different unique portion of the two-dimensional closed shape, and together the at least two pupils substantially fully forming the two-dimensional closed shape.

Abstract: Rotatable, oblique-viewing stereoendoscope including a dual-pupil aperture divided to a first pupil and a second pupil, a proximal objective assembly positioned proximally to the dual-pupil aperture, a first image sensor configured to detect a first image focused by the proximal objective assembly and a second image sensor configured to detect a second image focused by the proximal objective assembly, a relay system positioned distally to the dual-pupil aperture and a front optical system positioned distally to the relay system, the front optical system including a folding prism, wherein the front optical system is configured to reimage the dual-pupil aperture at a distal end thereof, thereby producing an image of the first pupil and an image of the second pupil at a distal pupil plane and wherein the stereoendoscope does not include a negative power lens positioned distally to the folding prism.

Abstract: A stereoscopic endoscope pupil configuration for embedding in a stereoscopic endoscope, the shape of the cross section of the stereoscopic endoscope is a predetermined closed two-dimensional shape, the stereoscopic endoscope pupil configuration including at least two pupils, each of the at least two pupils having a shape covering a different unique portion of the two-dimensional closed shape, and together the at least two pupils substantially fully forming the two-dimensional closed shape.

Abstract: Method for advancing a colonoscope within a colon of the body of a patient, the method including the procedures of acquiring a stereoscopic image pair of a region of the interior of the colon, identifying topographical features in the stereoscopic image pair, determining the depth of each of the topographical features in the stereoscopic image pair, and indicating the appropriate direction to advance the colonoscope, the direction being toward at least a selected one of the topographical features with greater depth than others of the topographical features.

Abstract: A system for video based registration between images during a skeletal medical procedure includes a stereoscopic camera, a two dimensional image detector and a registration processor. The camera is associated with a stereoscopic coordinate system, the camera acquires a stereoscopic image pair of fiducial marks fixed onto a skeletal structure. Fiducial representations of the fiducial marks appear on the stereoscopic image pair, and a skeletal representation of the skeletal structure appears on two different 2D images. The registration processor registers a stereoscopic coordinate system with a 3D coordinate system associated with a volumetric image detector, and superimposes 3D information on at least one volumetric image. The registration processor registers the stereoscopic coordinate system with the 3D coordinate system by registering the stereoscopic coordinate system with the 2D coordinate system and by registering the 2D coordinate system with the 3D coordinate system.

Abstract: A stereoscopic device including a sensor assembly for detecting a sequence of stereoscopic images of an object, a movement detector for detecting the movements of the sensor assembly relative to the object, and a processing unit connected to the sensor assembly and to the movement detector, wherein the processing unit selects portions of the stereoscopic images, according to a signal received from the movement detector, thereby producing a visually stable sequence of display images.

Abstract: Method for determining a disparity value of a disparity of each of a plurality of points on an object, the method including the procedures of detecting by a single image detector, a first image of the object through a first aperture, and a second image of the object through a second aperture, correcting the distortion of the first image, and the distortion of the second image, by applying an image distortion correction model to the first image and to the second image, respectively, thereby producing a first distortion-corrected image and a second distortion-corrected image, respectively, for each of a plurality of pixels in at least a portion of the first distortion-corrected image representing a selected one of the points, identifying a matching pixel in the second distortion-corrected image, and determining the disparity value according to the coordinates of each of the pixels and of the respective matching pixel.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: A stereoscopic endoscope employing a single light sensor array and a lenticular lens layer located at a proximal end of the endoscope, a pair of periscopic prisms located at a distal end of the endoscope and an optical relay assembly array located between the pair of periscopic prisms and the light sensor array. One prism of the pair of periscopic prisms receives a right view of an object and another prism of the pair receives a left view of the object. The interpupilar distance (IPD) between the right and left view is substantially large, thereby increasing the resolution of a stereoscopic image which is eventually displayed on a display. Another embodiment includes a set of three light sensor arrays, a light director and three lenticular lens layers. Each light sensor array detects light at a predetermined range of wavelengths (e.g. red, green and blue).

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: Method for determining a disparity value of a disparity of each of a plurality of points on an object, the method including the procedures of detecting by a single image detector, a first image of the object through a first aperture, and a second image of the object through a second aperture, correcting the distortion of the first image, and the distortion of the second image, by applying an image distortion correction model to the first image and to the second image, respectively, thereby producing a first distortion-corrected image and a second distortion-corrected image, respectively, for each of a plurality of pixels in at least a portion of the first distortion-corrected image representing a selected one of the points, identifying a matching pixel in the second distortion-corrected image, and determining the disparity value according to the coordinates of each of the pixels and of the respective matching pixel.