Abstract: A method implemented on a computing device having at least one processor, storage, and a communication platform connected to a network for determining blood pressure may include: receiving a request to determine blood pressure of a first subject from a terminal, obtaining data related to heart activity of the first subject, determining a personalized model for predicting blood pressure with respect to the first subject, determining the blood pressure of the first subject using the personalized model based on the data related to heart activity of the first subject, and sending the blood pressure of the first subject to the terminal in response to the request.