Abstract: An instrument produces clean and/or sterile products or compounds. The instrument includes a housing defining a clean interior. The housing has an inlet and a first HEPA filter for filtering an inflow through the inlet to create filtered air. A plurality of UV-C lights irradiate the interior. A 3D printer is in the interior to produce clean products. Preferably, the interior is CGMP compliant. The instrument may also have micro spray nozzles for spraying a sterilizing agent within the interior. A pressure pump can create a pressure differential, positive or negative, within the housing. Typically, the housing has an outlet with a second HEPA filter for filtering an outflow through the outlet to create environmentally safe air. An air circulator can create a laminar air flow through the housing.