Patents Assigned to Vitagenix, Inc.
  • Compositions and methods for inhibiting cox-2 expression and treating cox-2 associated disorders by using cox-2 antisense oligonucleotides
    Patent number: 6344323
    Abstract: The invention features antisense oligonucleotide molecules that specifically bind polynucleotides encoding COX-2. The present invention provides antisense oligonucleotides capable of inhibiting COX-2 expression, and methods of use thereof to reduce activity of COX-2 in tissues in order to treat diseases such as, for example, rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, chronic liver disease, ulcerative colitis, cell proliferative disorders, and inflammation associated with Alzheimer's Disease and stroke.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: February 5, 2002
    Assignee: Vitagenix, Inc.
    Inventor: Wilfried Seifert