Abstract: The present invention relates generally to the fields of immunology and vaccine technology. More specifically, the present invention relates to methods for freeze-drying biological preparations, including peptides, antigens, antibodies, and especially, cells. Importantly, the disclosed methods preserve the viability, infectivity and immunogenicity of cells from the Apicomplexa phylum, the Sarcocystidae family, and in particular, cells from the Toxoplasma genus.
Type:
Application
Filed:
May 13, 2015
Publication date:
March 30, 2017
Applicants:
MERIAL INC., VITAMFERO S.A, L'Universite De Bourgogne, L'Institut National Superieur des Sciences Agronom iques de L'Alimentation et de L'Environment
Inventors:
Noel Yves Henri Jean Genin, Jean-Christophe Audonnet, Didier Roy, Edouard Seche, Patrick Gervais, Samira Khaldi-Plassart, Romain Useo, Joelle DeConinck