Abstract: Described is a method for in vitro diagnosing whether a pregnant woman has a risk for developing preeclampsia (PE) comprising the steps of determining the afamin content of the pregnant woman in a blood sample or a blood-derived sample, urine, amniotic and cerebrospinal fluid; or determining the content of afamin m-RNA in a liver tissue sample; and comparing the afamin content determined in the sample with a reference value.
Type:
Application
Filed:
June 28, 2012
Publication date:
May 8, 2014
Applicant:
VITATEQ BIOTECHNOLOGY GMBH
Inventors:
Hans Dieplinger, Hannes Buchner, Christian Wadsack, Ludwig Wildt, Benjamin Dieplinger
Abstract: The present invention describes a method for diagnosing tumors of the reproductive organs which is characterized by determination of the afamin content in a sample of a body fluid or in a tissue sample, wherein a tumor is diagnosed if the afamin content in the sample is decreased compared to the afamin content in a sample from a person without a tumor of the reproductive organs.
Abstract: The invention relates to the use of afamin for the manufacture of a pharmaceutical preparation for the prevention or treatment of fertility disorders.
Type:
Application
Filed:
October 1, 2009
Publication date:
July 21, 2011
Applicant:
VITATEQ BIOTECHNOLOGY GMBH
Inventors:
Hans Dieplinger, Wolfgang Engel, Georg Wietzorrek
Abstract: There is disclosed a method of diagnosing early stage renal impairment in humans, characterized by the following steps: measuring the amount of apoA-IV in a body liquid or tissue sample of a human, and comparing the measured amount of apoA-IV with a reference value.
Abstract: The present invention describes a method for diagnosing tumours of the reproductive organs which is characterised by determination of the afamin content in a sample of a body fluid or in a tissue sample, wherein a tumour is diagnosed if the afamin content in the sample is decreased compared to the afamin content in a sample from a person without a tumour of the reproductive organs.
Abstract: Method for diagnosing a tumor in an individual comprising the following steps: —measuring the amount of apolipoprotein A-IV (ApoA-IV) in a body fluid sample or tissue sample of an individual, —comparing the measured amount of ApoA-IV in said sample with a reference value, wherein the reference value is the ApoA-IV content in a sample derived from an individual without a tumor, and —diagnosing a tumor if the ApoA-IV content in the sample is decreased compared to the reference value.
Abstract: The present invention describes a method for diagnosing tumours of the reproductive organs which is characterised by determination of the afamin content in a sample of a body fluid or in a tissue sample, wherein a tumour is diagnosed if the afamin content in the sample is decreased compared to the afamin content in a sample from a person without a tumour of the reproductive organs.
Abstract: Disclosed is a method for determining the fertility of mammals, in particular of humans, wherein
a body or organ fluid is taken from a mammal,
the afamin content is determined in this body or organ fluid, and
the determined afamin content is compared with a reference value so as to determine the fertility,
the use of afamin for determining the fertility of mammals, as well as a kit for carrying out this method.