Abstract: A method of processing a series of images of an embryo to determine estimated timings of developmental events for the embryo, wherein the method comprises: determining feature information for each image, the feature information for each image representing the content of the image; establishing machine learned classifiers for associating each image with a respective likelihood of the image being associated with one or more developmental events based on the feature information for the image; applying the machine learned classifiers to the feature information for each image to determine a respective likelihood of the image being associated with one or more developmental events, and determining estimated timings for the plurality of developmental events for the embryo from the respective likelihoods of the respective images being associated with respective ones of the plurality of developmental events. The method may further comprise determining an indication of a confidence estimate for the timings.

Abstract: An apparatus comprising a culture dish and a removable lid, wherein the culture dish comprises a main body having a side wall defining a reservoir region for receiving a quantity of liquid media, and the removable lid is arranged to cover the reservoir region during normal use, wherein the lid comprises a gas permeable material and includes an engagement portion formed of a resilient material adapted to cooperatively engage with the side wall of the main body of the culture dish so as to compress a part of the engagement portion of the removable lid against the side wall to form a vapour-tight seal for the reservoir region when the removable lid is coupled to the culture dish. The lid fitted to the culture dish enables a substantial portion of the culturing media to remain in the environment enclosed between the reservoir and the lid without use of a cover media to limit evaporation while allowing gaseous exchange therethrough.

Abstract: A method of processing a series of images of an embryo to determine estimated timings of developmental events for the embryo, wherein the method comprises: determining feature information for each image, the feature information for each image representing the content of the image; establishing machine learned classifiers for associating each image with a respective likelihood of the image being associated with one or more developmental events based on the feature information for the image; applying the machine learned classifiers to the feature information for each image to determine a respective likelihood of the image being associated with one or more developmental events, and determining estimated timings for the plurality of developmental events for the embryo from the respective likelihoods of the respective images being associated with respective ones of the plurality of developmental events. The method may further comprise determining an indication of a confidence estimate for the timings.

Abstract: A computer-implemented method, including the steps of: receiving video data of a human embryo, the video data representing a sequence of images of the human embryo in chronological order; applying at least one three-dimensional (3D) artificial neural network (ANN) to the video data to determine a viability score for the human embryo, wherein the viability score represents a likelihood that the human embryo will result in a viable embryo or a viable fetus; and outputting the viability score.

Abstract: An apparatus comprising a culture dish and a removable lid, wherein the culture dish comprises a main body having a side wall defining a reservoir region for receiving a quantity of liquid media, and the removable lid is arranged to cover the reservoir region during normal use, wherein the lid comprises a gas permeable material and includes an engagement portion formed of a resilient material adapted to cooperatively engage with the side wall of the main body of the culture dish so as to compress a part of the engagement portion of the removable lid against the side wall to form a vapour-tight seal for the reservoir region when the removable lid is coupled to the culture dish. The lid fitted to the culture dish enables a substantial portion of the culturing media to remain in the environment enclosed between the reservoir and the lid without use of a cover media to limit evaporation while allowing gaseous exchange therethrough.