Abstract: The invention relates to a package protecting its contents from the influence of light, microbial contamination and gas transport in either direction but which makes possible a visual control of the contents before the package is used.According to the invention, the package is made of a light-proof outer bag (1) and a light permeable inner bag (3) arranged inside the outer bag. The outer bag (1) and the inner bag (3) are each sealed at one of their ends (2,4) and are bonded around their periphery (6) close to their other end, and the two bags extend over this bond and are then commonly joined and sealed. By opening one of the end seals in the outer bag (1), the inner bag (3) can be turned out of the outer bag, and the contents (5) of the package can be observed visually through the inner bag.The package of the invention is especially suitable for storage of preparations for parenteral administration and especially infusion solutions intended to be given intravenously.
Abstract: Parenterally administrable oil-in-water emulsions formed from nutritive oils, such as soybean and sunflower oils, are improved first by treating the nutritive oil with silicic acid to remove undesirable components such as peroxides, pigments, thermal and oxidative decomposition products, certain unsaponifiable matter such as sterols, and polymers. Purification is effected by treating the oil with silicic acid or silica gel either directly, or as a solution thereof in a suitable solvent, such as hexane. Autoxidation of the purified oil is prevented by adding to the purified oil a tocopherol antioxidant, .gamma.-tocopherol being preferred. There is also added a metal scavenging agent such as ascorbyl palmitate.