Abstract: The present invention relates to high purity (?) Hydroxycitric acid metal salt derivatives of more than 98% purity having formula II (a-e), lla; X, 2X?Na Mb; X, 2X?K Hc; X?K, Y?Ca Hd1 X?Na, Y?Ca He; X=½Mg, Y?Mg and the method of preparation of high purity (?) hydroxycitric acid metal salt derivatives from (?) hydroxycitric acid lactone having formula (1) which in turn is isolated in a simple and efficient manner from dried rinds of the fruits of Garcinia species. This invention employs the HPLC method and optical rotation in assessing the purity (?) hydroxycitric acid and corresponding lactone (1).

Abstract: The present invention is directed in part towards methods of modulating the function of calcium channels with pyridine- or 1,4-dihydropyridine-based compounds. In addition, the invention describes methods of preventing and treating protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to pyridine- or 1,4-dihydropyridine-based compounds and pharmaceutical compositions comprising these compounds.

Abstract: The present invention relates to a process for the preparation of a water soluble inclusion complex of neem seed kernel extract (NSKE) containing azadirachtin-A in cyclodextrin and its use in an insecticidal formulation. The process of the present invention comprises the following steps adding neem seed kernel extract containing azadirachtin-A to cyclodextrin, the molar ratio of azadirachtin-A to the cyclodextrin ranging from 1:0.5 to 1:20, stirring the above mixture, filtering the above mixture to obtain a water soluble inclusion complex of neem seed kernel extract, if desired, freeze/spray drying the said water soluble complex of neem seed kernel extract to get a free flowing pale cream powder.

Abstract: The invention provides a protein precursor of a double-chain molecule having at least two polypeptide chains linked by two disulfide bonds. The precursor has the general formula B—Z—A wherein B and A are the two insulin polypeptide chains, and Z is a polypeptide comprising at least one site for proteolytic cleavage in a eukaryotic host cell transformed by DNA coding for the protein precursor or in a eukaryotic cell-free system, resulting in a secreted double-chain product consisting of the disulfide-bonded A and B chains in which a portion of the Z polypeptide is retained on the A chain and/or the B chain and can be removed therefrom by enzymatic or chemical agents in vitro. Preferably the B and A polypeptides are, respectively, the B- and A-chains of insulin linked by two disulfide bonds, and the mature insulin molecule is isolatable from the secreted double-chain product.

Abstract: The present invention is directed to a new soluble double metal salt of group IA and IIA of (-) hydroxycitric acid of general formula I:where X is IA group metal: Li or Na or K or Rb or Cs or Frwhere Y is IIA group metal: Be or Mg or Ca or Sr or Ba or Rawhere the concentration of X in the salt varies from 1.5-51.0%,the concentration of Y in the salts varies from 2.0-50.9%,the concentration of HCA in the salt varies from 31.0-93.0% depending on the nature of X and Y.This invention more particularly relates to new soluble double metal salt of group IA and IIA of (-) hydroxycitric acid of general formula II.

Abstract: This invention relates to a composition for controlling house dust mites. The composition comprises neem seed kernel extract containing azadirachtin, an alcoholic extract of plant resins, plant polyphenols or phenolic compound, fungistat used in food industry and a dispersion medium. The invention further includes a process of preparing the same by dispersing the above ingredients in a dispersion medium.

Abstract: Phosvitin or a modified phosvitin immobilised and coupled to a suitable matrix may be used for the separation and purification of proteins or polypeptides and in the removal of metal ions from biological material. If desired the phosvitin or modified phosvitin may be in the form of a metal chelate complex.

Abstract: A process of enriching hyroxycitric acid (HCA) from Garcinia rind in which a salt-free water extract of Garcinia rind is loaded onto an anion exchange column, eluted with a metal hydroxide for release of HCA. The water-extract is then treated with a cation exchange column to make free HCA as a free acid. The water extract is loaded at a capacity of 100 to 125% of the anion exchange column and at a capacity of 50 to 90% of the cation exchange column. The HCA can be added to food products such as beverages and snack bars.