Abstract: The present invention provides systems and methods for monitoring subjects, especially during sleep. Respiratory and sound data are recorded and coughs arousal are recognized as joint events in both of these signals having selected characteristics. Further, cough-arousal events during sleep are recognized when a likely cough occurs in association with a recognized EEG arousal. Cough arousal events are combined into a cough arousal index that reflects disease severity and sleep disruption due to cough. The methods of this invention are computer-implemented and can be provided as a program product including a computer readable medium. Measurements and indices provided by this invention can be used to monitor and to treat respiratory diseases.

Abstract: The present invention relates to the field of ambulatory and non-invasive monitoring of a plurality of physiological parameters of a monitored individual. The invention includes a physiological monitoring apparatus with an improved monitoring apparel worn by a monitored individual, the apparel having attached sensors for monitoring parameters reflecting pulmonary function, or parameters reflecting cardiac function, or parameters reflecting the function of other organ systems, and the apparel being designed and tailored to be comfortable during the individual's normal daily activities. The apparel is preferably also suitable for athletic activities. The sensors preferably include one or more ECG leads and one of more inductive plethysmographic sensor with conductive loops positioned closely to the individual to preferably monitor at least basic cardiac parameters, basic pulmonary parameters, or both.

Abstract: A method and system for extracting cardiac parameters from a plethysmographic signal is described wherein the plethysmographic signal is passed through a first filter to remove non-cardiac components of the signal. A second filter averages a plurality of cardiac cycles and cardiac parameters are extracted from the averaged cardiac signal.

Abstract: The present invention is directed to improved systems and methods for processing respiratory signals derived generally from respiratory plethysmography, and especially from respiratory inductive plethysmographic sensors mounted on a garment for ambulatory recording. The systems and methods provide improved signal filtering for artifact rejection, improved calibration of sensor data to produce outputs indicative of lung volumes. Further, this invention provides improved systems and methods directed to processing lung volume signals, however measured or derived, to provide improved determination of respiratory parameters and improved recognition of selected respiratory events.

Abstract: The present invention provides systems and methods for monitoring subjects, especially during sleep. Respiratory and sound data are recorded and coughs arousal are recognized as joint events in both of these signals having selected characteristics. Further, cough-arousal events during sleep are recognized when a likely cough occurs in association with a recognized EEG arousal. Cough arousal events are combined into a cough arousal index that reflects disease severity and sleep disruption due to cough. The methods of this invention are computer-implemented and can be provided as a program product including a computer readable medium. Measurements and indices provided by this invention can be used to monitor and to treat respiratory diseases.

Abstract: A method and system for extracting cardiac parameters from a plethysmographic signal is described wherein the plethysmographic signal is passed through a first filter to remove non-cardiac components of the signal. A second filter averages a plurality of cardiac cycles and cardiac parameters are extracted from the averaged cardiac signal.

Abstract: The present invention relates to the field of ambulatory and non-invasive monitoring of a plurality of physiological parameters of a monitored individual. The invention includes a physiological monitoring apparatus with an improved monitoring apparel worn by a monitored individual, the apparel having attached sensors for monitoring parameters reflecting pulmonary function, or parameters reflecting cardiac function, or parameters reflecting the function of other organ systems, and the apparel being designed and tailored to be comfortable during the individual's normal daily activities. The apparel is preferably also suitable for athletic activities. The sensors preferably include one or more ECG leads and one of more inductive plethysmographic sensor with conductive loops positioned closely to the individual to preferably monitor at least basic cardiac parameters, basic pulmonary parameters, or both.

Abstract: The present invention relates to the field of ambulatory and non-invasive monitoring of a plurality of physiological parameters of a monitored individual. The invention includes a physiological monitoring apparatus with an improved monitoring apparel worn by a monitored individual, the apparel having attached sensors for monitoring parameters reflecting pulmonary function, or parameters reflecting cardiac function, or parameters reflecting the function of other organ systems, and the apparel being designed and tailored to be comfortable during the individual's normal daily activities. The apparel is preferably also suitable for athletic activities. The sensors preferably include one or more ECG leads and one of more inductive plethysmographic sensor with conductive loops positioned closely to the individual to preferably monitor at least basic cardiac parameters, basic pulmonary parameters, or both.

Abstract: A method for calibrating non-invasive breathing monitors with sensors placed on the rib-cage and abdomen of a subject includes determining an initial scaling factor and an optimal multiplicative factor for the readings of the rib-cage and abdomen sensors using one of a least squares, linear regression, or multi-linear regression techniques. A current scaling factor is determined on a periodic basis using qualitative device calibration techniques. The current scaling factor is used to monitor breathing and diagnose obstructive apneas. Furthermore, the optimal multiplicative and the current scaling factor are used to determine the current tidal volume.

Abstract: A fabric for use in apparel of the type used for physiological monitoring of prescribed body functions has one or more elongated bands of elastic material which is stretchable in the longitudinal direction. Each such elastic band includes at least one conductive wire affixed to or formed therein in a curved pattern. A garment and a system of the type used for physiological monitoring of prescribed body functions includes such a fabric and a monitoring unit monitoring electrical parameters of the included conductive wires.