Abstract: A method for improving soft tissue attachment which includes the steps of coating a surface of a material, to which surface soft tissue is to be attached, with a coating rich in TiO2 and/or SiO2, and applying the coating where soft tissue attachment is desired. An implant in which a surface or surfaces of the implant intended to be attached to soft tissue are coated with a porous coating rich in TiO2 and/or SiO2, and the use of a porous surface coating rich in TiO2, SiO2, or TiO2 and SiO2, for the manufacture of an implant for soft tissue attachment are also disclosed.
Type:
Grant
Filed:
April 25, 2002
Date of Patent:
May 5, 2009
Assignee:
Vivoxid Oy
Inventors:
Timo Närhi, Hannu Paldan, Antti Yli-Urpo, Timo Peltola, Mika Jokinen, Risto-Pekka Happonen
Abstract: The invention relates to a medical device comprising non-sintered bioactive glass particles or fibres having a diameter in the range 5-100 ?m, bioactive glass comprising SiO2, Na2O, CaO, K2O, MgO, B2O3 and P2O5, wherein the amount of SiO2 is 50-65 wt-% of the final total weight, Na2O is 5-26 wt-% of the final total weight, CaO is 10-25 wt-% of the final total weight, K2O is 0-15 wt-% of the final total weight, MgO is 0-6 wt-% of the final total weight, B2O3 is 0-4 wt-% of the final total weight, and P2O5 is 0-4 wt-% of the final total weight, provided that the total amount of Na2O and K2O is 10-30 wt-% of the final total weight The device is essentially drug free. The invention also relates to the use of said composition for treating lesions associated with compromised or poor vascularisation and for preventing avascular fibrosis.
Type:
Application
Filed:
November 2, 2005
Publication date:
May 22, 2008
Applicant:
VIVOXID OY
Inventors:
Hannu Jarvelainen, Matti Laato, Jukka Salonen, Erik Vedel
Abstract: The invention relates to a heterophasic composition which essentially consists of three immniscible components, A, B and C, and the production method of the same. The component A is some body compatible polymer, the component H is a water soluble or hydrolytically degradable substance which produces cavities or network like porosity after disappearing through solubilization or degradation, and a bioactive substance C which at least component B contains in form of particles as a blend component and which still exists in the pores or their walls after the degradation or solubilization of the component B.
Type:
Grant
Filed:
July 12, 2001
Date of Patent:
March 6, 2007
Assignee:
Vivoxid Oy
Inventors:
Jukka Veli Seppälä, Riitta Minna Hannele Malin
Abstract: A bioactive glass composition which contains SiO2, Na2O, CaO, K2O, MgO, P2O5 and B2O3. The amount of SiO2 is 51-56 wt-% of the starting oxides, Na2O is 7-9 wt-% of the starting oxides, CaO is 21-23 wt-% of the starting oxides, K2O is 10-12 wt-% of the starting oxides, MgO is 1-4 wt-% of the starting oxides, P2O5 is 0.5-1.5 wt-% of the starting oxides, B2O3 is 0-1 wt-% of the starting oxides, provided that the total amount of Na2O and K2O is 17-20 wt-% of the starting oxides. Also disclosed is the manufacture and use of the bioactive glass composition.
Type:
Application
Filed:
October 2, 2003
Publication date:
July 27, 2006
Applicant:
Vivoxid Oy
Inventors:
Heimo Ylanen, Antti Yli-Urpo, Mikko Hupa