Abstract: A series of genes from Streptococcus pyogenes are shown to encode products which are implicated in virulence. The identification of these genes therefore allows attenuated microorganisms to be produced. Furthermore, the genes or their encoded products can be used in the manufacture of vaccines for therapeutic application.
Type:
Grant
Filed:
December 22, 2000
Date of Patent:
October 4, 2005
Assignee:
VMAX Ltd.
Inventors:
Enda Elizabeth Clarke, Liqing Zhou, Jacqueline Elizabeth Shea, Robert Graham Feldman, David William Holden