Abstract: Microfluidic chips and cartridges and systems that include such chips are disclosed. In some embodiments, the chips include a microfluidic channel disposed in a substrate with the channel comprising at least one expansion region. The channel is configured to generate a vortex within the at least one expansion region in response to fluid through the microfluidic channel to trap cells or particles. The substrate in which the channel is formed may be relatively rigid to resist deformation.
Type:
Grant
Filed:
April 17, 2017
Date of Patent:
October 29, 2024
Assignee:
Vortex Biosciences, Inc.
Inventors:
Elodie Sollier, Michael Lee Kochersperger, Robert F. Englert, James Che, Kuo-Wei Huang, Michael Boyce-Jacino, Anatasia Neddersen, Anna Passernig, Bruce Richardson, Insang Choi