Patents Assigned to VPS-3, INC.
  • Antifungal compounds and processes for making
    Patent number: 10308632
    Abstract: Provided are polymorphic forms of compound 5 or 5*, or mixtures thereof, and polymorph forms of compound 14 or 14*, or mixtures thereof. Also provided are methods of preparing compound 5 or 5*, or mixtures thereof, and methods of preparing compound of 14 or 14*, or mixtures thereof, which are useful as antifungal agents. In particular, provided is new methodology for preparing polymorphs of the compounds described and substituted derivatives thereof.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: June 4, 2019
    Assignee: VPS-3, Inc.
    Inventors: David Dale Wirth, Christopher M. Yates
  • METALLOENZYME INHIBITOR COMPOUNDS
    Publication number: 20180256572
    Abstract: Provided are compounds having HDAC6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by HDAC6.
    Type: Application
    Filed: March 9, 2018
    Publication date: September 13, 2018
    Applicant: VPS-3, Inc.
    Inventor: Christopher M. Yates
  • 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1H-tetrazol-1-yl)propan-2-ols and processes for their preparation
    Patent number: 9988365
    Abstract: Provided herein are 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1H-tetrazol-1-yl)propan-2-ols and 1-(2,4-difluorophenyl)-2,2-difluoro-2-(5-substituted-pyridin-2-yl)ethanones and processes for their preparation.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: June 5, 2018
    Assignee: VPS-3, Inc.
    Inventors: William J. Hoekstra, Nakyen Choy, Carl DeAmicis, Daniel Knueppel, Jim Renga, Michael T. Sullenberger, Gregory Whiteker, Yuanming Zhu, Gary D. Gustafson
  • Metalloenzyme inhibitor compounds
    Patent number: 9938255
    Abstract: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: April 10, 2018
    Assignee: VPS-3, Inc.
    Inventors: William J. Hoekstra, Christopher M. Yates
  • 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1H-tetrazol-1-yl)propan-2-ols and processes for their preparation
    Patent number: 9914726
    Abstract: Provided herein are 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1H-tetrazol-1-yl)propan-2-ols and processes for their preparation.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: March 13, 2018
    Assignee: VPS-3, INC.
    Inventors: William J. Hoekstra, Daniel Knueppel, Jim Renga, Gregory Whiteker, Michael T. Sullenberger