Abstract: Indoor mapping and modular control for UAVs and other autonomous vehicles, and associated systems and methods. A representative unmanned aerial vehicle system includes a body, a propulsion system carried by the body, a sensor system carried by the body, and a controller carried at least in part by the body and operatively coupled to the propulsion system and the sensor system. The controller is programmed with instructions that, when executed, operate in a first autonomous mode and a second autonomous mode. In the first autonomous mode, the instructions autonomously direct the propulsion system to convey the body along a first route within an indoor environment. While the body travels along the first route, the instructions receive inputs from the sensor system corresponding to features of the indoor environment. The features are stored as part of a 3-D map.