Abstract: A mutant Pichia pastoris alcohol oxidase 1 (AOX1) promoter of the wild type Pichia pastoris AOX1 promoter (SEQ ID No. 1) comprising at least one mutation selected from the group consisting of: a) a transcription factor binding site (TFBS), b) nucleotides 170 to 235 (?784 to ?719), nucleotides 170 to 191 (?784 to ?763), nucleotides 192 to 213 (?762 to ?741), nucleotides 192 to 210 (?762 to ?744), nucleotides 207 to 209 (?747 to ?745), nucleotides 214 to 235 (?740 to ?719), nucleotides 304 to 350 (?650 to ?604), nucleotides 364 to 393 (?590 to ?561), nucleotides 434 to 508 (?520 to ?446), nucleotides 509 to 551 (?445 to ?403), nucleotides 552 to 560 (?402 to ?394), nucleotides 585 to 617 (?369 to ?337), nucleotides 621 to 660 (?333 to ?294), nucleotides 625 to 683 (?329 to ?271), nucleotides 736 to 741 (?218 to ?213), nucleotides 737 to 738 (?217 to ?216), nucleotides 726 to 755 (?228 to ?199), nucleotides 784 to 800 (?170 to ?154) or nucleotides 823 to 861 (?131 to ?93) of Seq ID No.

Abstract: Cooling medium comprising an ionic liquid with a hydrogen content of 0% to 8.5% by weight and its use.

Abstract: A method of synthesizing organic molecules is provided, wherein the method comprises providing an electrophilic educt, providing an ionic liquid comprising a carbanion, and synthesizing the organic molecules by mixing the electrophilic educt and the ionic liquid.

Abstract: A method of impeding water input in an ionic liquid is provided, wherein the method comprises adding an additive to the ionic liquid wherein the additive comprises an orthoester. In particular, at least some residues of the additive may remain or may be present in the ionic liquid during the usage of the ionic liquid. For example, the additive may be formed by the orthoester or by a mixture of orthoesters.

Abstract: A method for sorbing a gas using an ionic liquid to sorb a vapor having an electric multi-pole moment. The ionic liquid comprises an anion and a cation. The electric multi-pole moment may be an electric dipole moment and/or an electric quadru-pole moment. The sorption may be an adsorption or an absorption. The ionic liquid may be a liquid that substantially contains only anions and cations, while not containing other components, such as water. Alternatively, a solution containing the ionic liquid and a solvent or further compound, such as water, may be used.

Abstract: A thin-film evaporator with a vertical drum (1), a supply line (4) that is arranged in the upper region of the drum (1) and is used to supply a medium to be evaporated, a heating jacket (3) arranged on the periphery of the drum and forming vapors, a discharge line (20) for discharging the residue left in the lower end of the drum, and a condenser (11) supplied with a coolant, for increasing the separating capacity and optionally for performing chemical reactions, is characterized in that an inner device (24) influencing the action of the thin-film evaporator is provided in the path of the vapors from the heating jacket (3) to the condenser (11).